ID I0L0G5_9ACTN Unreviewed; 722 AA.
AC I0L0G5;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Zinc-binding dehydrogenase {ECO:0000313|EMBL:CCH17312.1};
GN ORFNames=MILUP08_42233 {ECO:0000313|EMBL:CCH17312.1};
OS Micromonospora lupini str. Lupac 08.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1150864 {ECO:0000313|EMBL:CCH17312.1, ECO:0000313|Proteomes:UP000003448};
RN [1] {ECO:0000313|Proteomes:UP000003448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lupac 08 {ECO:0000313|Proteomes:UP000003448};
RX PubMed=22815450; DOI=10.1128/jb.00628-12;
RA Alonso-Vega P., Normand P., Bacigalupe R., Pujic P., Lajus A., Vallenet D.,
RA Carro L., Coll P., Trujillo M.E.;
RT "Genome Sequence of Micromonospora lupini Lupac 08, Isolated from Root
RT Nodules of Lupinus angustifolius.";
RL J. Bacteriol. 194:4135-4135(2012).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH17312.1}.
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DR EMBL; CAIE01000017; CCH17312.1; -; Genomic_DNA.
DR RefSeq; WP_007457883.1; NZ_HF570108.1.
DR AlphaFoldDB; I0L0G5; -.
DR STRING; 1150864.MILUP08_42233; -.
DR eggNOG; COG0673; Bacteria.
DR eggNOG; COG1063; Bacteria.
DR OrthoDB; 179913at2; -.
DR Proteomes; UP000003448; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR CDD; cd08255; 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43350:SF22; D-GULOSIDE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003448}.
FT DOMAIN 179..297
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
FT DOMAIN 390..510
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 536..635
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 722 AA; 76469 MW; A2EB70B64748D10B CRC64;
MKQIVQSVSG GELRVVEVPQ PEPGATEVLV ATRRSLLSAG TERAVRELAS ASLLRKARAR
PDLVRQVVNR ARTGGVRSTL AAVRSRLDED MPLGYSAAGV VVTAGAATDG LRPGMRVATA
SAGHAEYQAV PGLLAVPVPD AVSDQAAAFG AVAAIALQGL RQAEVGVGGS VAVVGLGLVG
QLTVRLALAS GLTVVGIDLR GWTAELAGGA GALGLVEAGA ATTEQVMEAT RGRGVDAVLI
TAATTSSEPV ARSAEIARDR ARLVVVGDVG LDLDRRRFYE RELDLRFARS YGPGRYDRAY
EEWGVDYPIG HVRWTARRNV ETYLDLVASG RVAVDDMVTH VFDVERATSA YEVLASDPRS
LAVQLTYSAP AQPTSRVATI RPRHRSTSPR AGLIGAGTYA KATFLPALKA AGWGDDLAAI
TSAKGLSARH AAERNDIAVV APTVEDLLAR DDVDVAFVLS RHDSHAELAV RALDAGKHVF
VEKPLALTRD ELDDVLAAYD RNPGHLFVGF NRRHAPMVAY TRKVLTAGSG PITIAYRVNA
GQLPAAHWYH DRRQGGRVRG EVCHFIDLAS WLVGEQPRVV HAYGSGRGEP GLEEDVSVLL
GYPDGSTATI TYSTRGHRRT PKERLEILGR GHTVLIDDFR RLEVDGREVK RAPGGKGHQE
QLAHVRAVIT GNAPHQRGFE ASIGTTEAAL SAVAALAGIP QLPARLPTQI DVDSGVNAGI
SS
//
