ID I0L4A4_9ACTN Unreviewed; 378 AA.
AC I0L4A4;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Methyltransferase type 11 {ECO:0000313|EMBL:CCH18651.1};
GN ORFNames=MILUP08_43562 {ECO:0000313|EMBL:CCH18651.1};
OS Micromonospora lupini str. Lupac 08.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1150864 {ECO:0000313|EMBL:CCH18651.1, ECO:0000313|Proteomes:UP000003448};
RN [1] {ECO:0000313|Proteomes:UP000003448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lupac 08 {ECO:0000313|Proteomes:UP000003448};
RX PubMed=22815450; DOI=10.1128/jb.00628-12;
RA Alonso-Vega P., Normand P., Bacigalupe R., Pujic P., Lajus A., Vallenet D.,
RA Carro L., Coll P., Trujillo M.E.;
RT "Genome Sequence of Micromonospora lupini Lupac 08, Isolated from Root
RT Nodules of Lupinus angustifolius.";
RL J. Bacteriol. 194:4135-4135(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH18651.1}.
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DR EMBL; CAIE01000027; CCH18651.1; -; Genomic_DNA.
DR AlphaFoldDB; I0L4A4; -.
DR STRING; 1150864.MILUP08_43562; -.
DR eggNOG; COG2227; Bacteria.
DR Proteomes; UP000003448; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR020803; PKS_MeTfrase.
DR InterPro; IPR048711; Rv2258c-like_HTH.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45128; METHYLTRANSFERASE TYPE 11; 1.
DR PANTHER; PTHR45128:SF1; METHYLTRANSFERASE TYPE 11; 1.
DR Pfam; PF21320; HTH_65; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR SMART; SM00828; PKS_MT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:CCH18651.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003448};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CCH18651.1}.
FT DOMAIN 174..378
FT /note="Polyketide synthase methyltransferase"
FT /evidence="ECO:0000259|SMART:SM00828"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 40101 MW; D16B8B7DCD27C279 CRC64;
MTGRPGHAPG TATLRPPPPG EPDQRARALS LRLFLAMLHT QELLAGYLGA RLGLYEALDR
GPADVAELCA RTGIDPRYAR EWLEQQAVAG FVDVDDVTAA PERRVYRLPP GHAEVLLASD
SPLSLVSLTM LPLGGVAGAL PALLEAYRTG AGVPDDVYGD DWRHGHSGAN RALFTYSLPG
WLATALPQLH QRLAAAPSRI ADIGCGAGWA AIALARAYPL AEVDGYDLDA PTVAAAQANA
ASAGVADRVR FHRRDAADPE LAGRYDLVCV FDALHEMSQP VSVLAACRRL RADGGAVLVL
DAKVAHRFVA PGDEVERFQY ATSVLHCLPA GLAAPNSTAS GTVLRPAQVR RFATGAGFAD
VQIVPVDDRF HRLYHLTG
//
