ID I0L800_9ACTN Unreviewed; 352 AA.
AC I0L800;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:CCH19947.1};
GN ORFNames=MILUP08_44827 {ECO:0000313|EMBL:CCH19947.1};
OS Micromonospora lupini str. Lupac 08.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1150864 {ECO:0000313|EMBL:CCH19947.1, ECO:0000313|Proteomes:UP000003448};
RN [1] {ECO:0000313|Proteomes:UP000003448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lupac 08 {ECO:0000313|Proteomes:UP000003448};
RX PubMed=22815450; DOI=10.1128/jb.00628-12;
RA Alonso-Vega P., Normand P., Bacigalupe R., Pujic P., Lajus A., Vallenet D.,
RA Carro L., Coll P., Trujillo M.E.;
RT "Genome Sequence of Micromonospora lupini Lupac 08, Isolated from Root
RT Nodules of Lupinus angustifolius.";
RL J. Bacteriol. 194:4135-4135(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH19947.1}.
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DR EMBL; CAIE01000037; CCH19947.1; -; Genomic_DNA.
DR AlphaFoldDB; I0L800; -.
DR STRING; 1150864.MILUP08_44827; -.
DR eggNOG; COG1609; Bacteria.
DR OrthoDB; 252678at2; -.
DR Proteomes; UP000003448; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000003448};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 329..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 36456 MW; AAD847585B657A3D CRC64;
MATMHDVARL AGVSPSTVSY VLTGTRPISQ ATRDKVLAAM AQLDYQPNAM ARGLASRRSR
ILGLLMPMDE RGLGATETAF VTGAAAAASA VGYHLVLSPV GGGNLDDLRR LASQRMLDGV
VLMEVQLADE RVTVLQEAGV PLVLIGRTGD TTGLSYVDID FEQTVREAVA HLVGLGHRRI
VYVNHSAATL ASGYGPALRT RDAFVSAMSG HGLEPVMIPA EDSAAGGRAA LAAAFARTPG
LTAVVAMNET AIFGILGELT GRGLSVPDDV SVVSMVTSPQ VAELATPALT AMTSPGSTLG
RIAIEALVRH LDGRGNERHQ QLLPCALEIR GSTAEPRRPA PASAEPSPTS GG
//
