ID I0QU31_9GAMM Unreviewed; 761 AA.
AC I0QU31;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:EIC84804.1};
GN ORFNames=SPM24T3_10166 {ECO:0000313|EMBL:EIC84804.1};
OS Serratia sp. M24T3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=932213 {ECO:0000313|EMBL:EIC84804.1, ECO:0000313|Proteomes:UP000011072};
RN [1] {ECO:0000313|EMBL:EIC84804.1, ECO:0000313|Proteomes:UP000011072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M24T3 {ECO:0000313|EMBL:EIC84804.1,
RC ECO:0000313|Proteomes:UP000011072};
RX PubMed=22740681; DOI=10.1128/JB.00670-12;
RA Proenca D.N., Espirito Santo C., Grass G., Morais P.V.;
RT "Draft Genome Sequence of Serratia sp. Strain M24T3, Isolated from Pinewood
RT Disease Nematode Bursaphelenchus xylophilus.";
RL J. Bacteriol. 194:3764-3764(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIC84804.1}.
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DR EMBL; AJHJ01000009; EIC84804.1; -; Genomic_DNA.
DR RefSeq; WP_009636637.1; NZ_AJHJ01000009.1.
DR AlphaFoldDB; I0QU31; -.
DR STRING; 932213.SPM24T3_10166; -.
DR PATRIC; fig|932213.3.peg.2056; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000011072; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 517..696
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 761 AA; 85474 MW; 7E03722EA8768E9C CRC64;
MITITLTQAA LALVAGILPL TVLPALPGLY SGITLFVIAC IAGSLPYHFS KLLSVALLGL
LWATFNAQQI LQQTSALVGN RQQVVATVSS SYLQKEESHK VVLTLKEVNG QRVFPPLTVK
VSSDGFPGGY CAGQNWLLTM SLRPVHSQLN LASFDAQRWA VANRQTLRGS IRSAGLLSGE
CSIRQEKINV ASGQLAGLKN MPVLLALAFG ERGLIDQKTL QLFKVTGTAH LMAISGLHIG
VAALIGWLSA RGLQFLLPLR LIDYRFPILL SWLAMAYYTW LSGLNPPAMR AALAITLWLV
LRLCKVRSDP WQVWSWGVAL LMVSDPLGIL SDSFWLSCFA VAGLIFWFQW APLPSRYSRH
WYWAWGRWGH LQAGMTFLLL PMQIGLFHGL SSASFVANLW AVPIVSLFTV PLVLLALFLN
HFPYDLAQPL IDLLWLLADH SLKWVVAGLQ RVEHYWLPLG ETSVALSFSG WIAVIVWRMG
WFKTHYTSVM ALCGLMLLWR QTTNKENWRL DMLDVGHGLA ILIEKNGRGV LYDTGNRWEG
GSQAQMQILP YLQWRNIDLD QIIVSHSHMD HHGGTELVKA AFPAAIVRSS FIGNRPCIKG
QIWHWQSLRF EVLWPLTLKE YANNNDSCVI KVSDGRFSVL LSGDIEKEAE MQLVRENRKN
LRVNLLQVPH HGSNTSSIGP FLRATGAEVA IASAARFNVW RLPAEKIKQR YRKNGVIWRD
TARSGQLSAF FFNNHWVVKG LREQLMPRWY HQWFGVRGDN E
//
