ID   I0R031_9MICO            Unreviewed;       599 AA.
AC   I0R031;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00032875};
GN   ORFNames=IMCC13023_07700 {ECO:0000313|EMBL:EIC91217.1};
OS   Candidatus Aquiluna sp. IMCC13023.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Luna cluster; Luna-1 subcluster; Aquiluna.
OX   NCBI_TaxID=1081644 {ECO:0000313|EMBL:EIC91217.1, ECO:0000313|Proteomes:UP000054510};
RN   [1] {ECO:0000313|Proteomes:UP000054510}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMCC13023 {ECO:0000313|Proteomes:UP000054510};
RX   PubMed=22689238; DOI=10.1128/JB.00586-12;
RA   Kang I., Lee K., Yang S.J., Choi A., Kang D., Lee Y.K., Cho J.C.;
RT   "Genome sequence of "Candidatus Aquiluna" sp. strain IMCC13023, a marine
RT   member of the Actinobacteria isolated from an arctic fjord.";
RL   J. Bacteriol. 194:3550-3551(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIC91217.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJKR01000003; EIC91217.1; -; Genomic_DNA.
DR   RefSeq; WP_007541483.1; NZ_AJKR01000003.1.
DR   AlphaFoldDB; I0R031; -.
DR   STRING; 1081644.IMCC13023_07700; -.
DR   PATRIC; fig|1081644.3.peg.777; -.
DR   eggNOG; COG1022; Bacteria.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000054510; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd05907; VL_LC_FACS_like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43272:SF83; ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J; 1.
DR   PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EIC91217.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054510}.
FT   DOMAIN          27..425
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   599 AA;  65486 MW;  F637DEE34D0B3DED CRC64;
     MKFYDVPIKV NTDPSLNASD LLLERVAINP SHPLFSRQNP DGTWRDVTSQ EFLDEVKSLA
     KGLIAQGIKP GDAVAIMSRT RYEWTMIDFA IWFAGAIGVP IYESSSASQI EWILTDSDAI
     ALFIEDDEHL ERFNQVKSGT QKVKHVWRID SKDFSGLHQD GEKIGDDQLE KARSHANLSD
     LATIVYTSGT TGNPKGCELT HKSFVDHAKN AAAEIPEIAN DKQSSLIFLP LAHILARYVS
     VLCLHSGIRV GHLSDSLQVA QVLPAFKPTF ILAVPRVFEK IYNGAELRAE TGGKGKIFRS
     AAEVAIDYSK ALDSKSGPSL GLKVKHKLFD RLVYGKLRAA MGGNVKYAIS GGAPLGARLG
     HFYRGIGLIV LEGYGLTETA AAAVIGRVAW QKIGKVGRAL PGTGIKIAED GEIWLRGINC
     MRGYWRNEAA TREAFDGDWF RTGDLGELDE DGFLTITGRK KEMLVTAGGK NVAPAPIEDP
     LRAHPLVGQV VVIGDSKPFI SALISLDPDM VMVWAQNNGI EEKLTLAEAT KHPTVIAEIQ
     KTVDEVNKLF SKAEQVRSFE ILDVELTEAS GHLTPSLKIK RSKVMTDFDL QVGRIYASA
//