ID I0R0V3_9MICO Unreviewed; 680 AA.
AC I0R0V3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Ribonuclease G and E {ECO:0000313|EMBL:EIC91489.1};
DE EC=3.1.26.12 {ECO:0000313|EMBL:EIC91489.1};
GN ORFNames=IMCC13023_10420 {ECO:0000313|EMBL:EIC91489.1};
OS Candidatus Aquiluna sp. IMCC13023.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Luna cluster; Luna-1 subcluster; Aquiluna.
OX NCBI_TaxID=1081644 {ECO:0000313|EMBL:EIC91489.1, ECO:0000313|Proteomes:UP000054510};
RN [1] {ECO:0000313|Proteomes:UP000054510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC13023 {ECO:0000313|Proteomes:UP000054510};
RX PubMed=22689238; DOI=10.1128/JB.00586-12;
RA Kang I., Lee K., Yang S.J., Choi A., Kang D., Lee Y.K., Cho J.C.;
RT "Genome sequence of "Candidatus Aquiluna" sp. strain IMCC13023, a marine
RT member of the Actinobacteria isolated from an arctic fjord.";
RL J. Bacteriol. 194:3550-3551(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIC91489.1}.
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DR EMBL; AJKR01000003; EIC91489.1; -; Genomic_DNA.
DR AlphaFoldDB; I0R0V3; -.
DR STRING; 1081644.IMCC13023_10420; -.
DR PATRIC; fig|1081644.3.peg.1052; -.
DR eggNOG; COG1530; Bacteria.
DR OrthoDB; 9804278at2; -.
DR Proteomes; UP000054510; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EIC91489.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054510};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 206..283
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 75241 MW; 7E24CB064F5C894A CRC64;
MAEKKEIPEK TTSKKAPAKK VAEKKAVEKK IVDKKIVDKK PAAKKEASTK VVEKKDEPKK
PLSIQLLFQA PDLPTPKVNP RSGKLAEEET SEAATRSAPT KSASTRTRQR SKPESEAKPK
TNDEPAEEKD SGSTRVAAKR QRRKDSRDTG RRRTAVTESE FLARRESVDR RMVVREKDAR
VQIGVLEDGL LVEHYVAESQ GGSLIGNVYL GKVQNVLPSM EAAFVDIGRG RNAVLYSGEV
DWDAAETGNQ PRRIELALKS GDQVLVQVTK DPVGQKGARL TSQISLPGRF LVYVPGGNMS
GISRKLPEGE RQRLKQILKH ALPEDAGVIV RTAAEGATED QLTLDVERLK MQWENINSEV
AKGKAPTLLH SEPDLLVKII RDVFNEDFTE LVVSGEESLE TIRQYLESVA PELIERLVQF
TASEDVFDSY RLGDQIIKAL DRKVFLPSGG SLVIDRTEAM TVVDVNTGKF IGSGGNLEET
VTKNNLEAAE ELVRQLRLRD IGGIVVVDFI DMIQESNQEM VRRRLLECLS RDRTKNQVGE
ITSLGLVQMT RKKIGLGLLE TFSEPCDCCA GRGVVVHDEP RFRMPEVSEN KRTKKKEKTK
PTVVKKVVTA EQADAFKNVV NQIASAGHSS DEALLQLKKE PEGKTEILNA VLDSLPEAEN
VPKPKRRRAT SAGKLSTTTE
//
