ID I0RB32_9FIRM Unreviewed; 250 AA.
AC I0RB32;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Cobalt transport protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE Short=ECF transporter S component CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN Name=cbiM {ECO:0000256|HAMAP-Rule:MF_01462,
GN ECO:0000313|EMBL:EIC96890.1};
GN ORFNames=HMPREF9970_1120 {ECO:0000313|EMBL:EIC96890.1};
OS Lachnoanaerobaculum saburreum F0468.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=1095750 {ECO:0000313|EMBL:EIC96890.1, ECO:0000313|Proteomes:UP000005039};
RN [1] {ECO:0000313|EMBL:EIC96890.1, ECO:0000313|Proteomes:UP000005039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0468 {ECO:0000313|EMBL:EIC96890.1,
RC ECO:0000313|Proteomes:UP000005039};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC CbiMNOQ involved in cobalt import. {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC (S components, CbiM and CbiN) of unknown stoichimetry.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01462};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01462}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CbiM family. {ECO:0000256|HAMAP-
CC Rule:MF_01462}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIC96890.1}.
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DR EMBL; AJGH01000022; EIC96890.1; -; Genomic_DNA.
DR RefSeq; WP_008753062.1; NZ_AJGH01000022.1.
DR AlphaFoldDB; I0RB32; -.
DR PATRIC; fig|1095750.3.peg.379; -.
DR eggNOG; COG0310; Bacteria.
DR OrthoDB; 9809846at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000005039; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.1760.20; -; 1.
DR HAMAP; MF_01462; CbiM; 1.
DR InterPro; IPR018024; CbiM.
DR InterPro; IPR002751; CbiM/NikMN.
DR NCBIfam; TIGR00123; cbiM; 1.
DR PANTHER; PTHR43627; -; 1.
DR PANTHER; PTHR43627:SF1; COBALT TRANSPORT PROTEIN CBIM; 1.
DR Pfam; PF01891; CbiM; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285, ECO:0000256|HAMAP-Rule:MF_01462};
KW Cobalt transport {ECO:0000256|ARBA:ARBA00022426, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01462};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01462}.
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 105..128
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 166..193
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 205..231
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
SQ SEQUENCE 250 AA; 26588 MW; 70CF727FCD1CA1D0 CRC64;
MKRKEKNFIV LAILFAFSFA LPFNSNAMHI MEGYLPVGYC VAWGLISLPF LIAGYLSVKK
TVSKDRRSIT LIAMSGAFVF VLSSLKIPSV TGSCSHMTGT GLAAILFGPS AVSILGIIVL
IFQAILLAHG GITTLGANTF SMAIAGPFVS YVVYKICKKA KVSDNISIFL AAFLGDLLTY
VVTSFQLALA YPMKQGGIMA SAGKFLLVFA PTQVPLAIIE GLLTVVIIIG LRTYAKSELK
EIGFLEGGAN
//
