ID   I0T9D4_9BACT            Unreviewed;       376 AA.
AC   I0T9D4;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Pyridoxal phosphate biosynthetic protein PdxA {ECO:0000313|EMBL:EID32237.1};
DE            EC=1.1.1.262 {ECO:0000313|EMBL:EID32237.1};
GN   Name=pdxA {ECO:0000313|EMBL:EID32237.1};
GN   ORFNames=HMPREF9969_0913 {ECO:0000313|EMBL:EID32237.1};
OS   Prevotella sp. oral taxon 306 str. F0472.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1095752 {ECO:0000313|EMBL:EID32237.1, ECO:0000313|Proteomes:UP000004421};
RN   [1] {ECO:0000313|EMBL:EID32237.1, ECO:0000313|Proteomes:UP000004421}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0472 {ECO:0000313|EMBL:EID32237.1,
RC   ECO:0000313|Proteomes:UP000004421};
RA   Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA   Nelson K.E.;
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EID32237.1}.
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DR   EMBL; AJIN01000072; EID32237.1; -; Genomic_DNA.
DR   RefSeq; WP_009436095.1; NZ_AJIN01000072.1.
DR   AlphaFoldDB; I0T9D4; -.
DR   STRING; 1095752.HMPREF9969_0913; -.
DR   PATRIC; fig|1095752.3.peg.2489; -.
DR   eggNOG; COG1995; Bacteria.
DR   OrthoDB; 9801783at2; -.
DR   Proteomes; UP000004421; Unassembled WGS sequence.
DR   GO; GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR005255; PdxA_fam.
DR   PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR   Pfam; PF04166; PdxA; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:EID32237.1}.
FT   REGION          353..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  42349 MW;  B6CC28D1CB1F46FE CRC64;
     MNENKRVRVA ITHGDTNGVG YELIFKTFSE PDMLELCTPI IYGSPKVATY HRNALEMEAN
     FTIINDASEA KEGRLNLLPV FDEEIKVELG VASEESGEAG LKAIDKALED YRQGLFDVLV
     TAPIDNNDKF HFCGQSRYIE DHLETEGNGL SIFIHEGLRV ALATRNLPLR QVADSISKES
     IENKTKELFQ SLRRDFRISC PRIAILGLNP KAGDNGLLGS EEEEVIMPAI NELVEKEIQV
     FGPYAADTFF SNGDYQEFDG VLAMYYEQGL SPFRTLSDFQ GINYTSGMSL VRTAAEIPNS
     LAIAGQGVAN EQAFRHAIYL AIDIFRNRAE YDEALVHPLP KLYKEKRDES DKVRFAIPHK
     REDRTPHSER HEEKRG
//