ID I0T9S6_9BACT Unreviewed; 705 AA.
AC I0T9S6;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Transporter, CPA2 family {ECO:0000313|EMBL:EID32379.1};
GN ORFNames=HMPREF9969_0928 {ECO:0000313|EMBL:EID32379.1};
OS Prevotella sp. oral taxon 306 str. F0472.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1095752 {ECO:0000313|EMBL:EID32379.1, ECO:0000313|Proteomes:UP000004421};
RN [1] {ECO:0000313|EMBL:EID32379.1, ECO:0000313|Proteomes:UP000004421}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0472 {ECO:0000313|EMBL:EID32379.1,
RC ECO:0000313|Proteomes:UP000004421};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EID32379.1}.
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DR EMBL; AJIN01000069; EID32379.1; -; Genomic_DNA.
DR RefSeq; WP_009751936.1; NZ_AJIN01000069.1.
DR AlphaFoldDB; I0T9S6; -.
DR STRING; 1095752.HMPREF9969_0928; -.
DR PATRIC; fig|1095752.3.peg.2350; -.
DR eggNOG; COG0475; Bacteria.
DR eggNOG; COG0589; Bacteria.
DR OrthoDB; 9793589at2; -.
DR Proteomes; UP000004421; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.12370; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43562:SF4; NA(+)_H(+) ANTIPORTER NHAS5; 1.
DR PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..392
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 705 AA; 80049 MW; C67CBC4BCBC7259D CRC64;
MLHLSQYFPI ADPTLIFFVV LLMILISPII MGRLRIPHII GMVLAGVIVG KYGLNILERD
ASFELFGRVG LYYIMFLAGL EMDMEGLKKN RNRVMIFGLL TFLCPFIMTY LMGVSLLSYT
PLAALLLAAI MASNTLIAYP IVGRYGLTRH TSSTLSVGSS MMALFIALIV MASIVNSYHG
GGGVGFWLFF VVKFVVYCAG LIFFIPRLAR WFLRRYSDAV MQFIFILAVV FLSASLSDAV
GLEGIFGAFL SGLILNRYVP KVSPLMNRIE FTGNALFIPY FLIGVGMLIN VRLLFSGTNI
LWVVFCLVVF GTLGKAVAAY IAARLFKMSK MSGHMMFGLT SAHAAGAIAM VMVGRRLEIS
PGVYLFGDEV LNGIVIMILF TCIISTLVTE WAAQRIRLQE KEEPEMVKTL NDEKILIPVK
YPEYAESLVS MAIMMRNPRL KKELVALNVV YDDVNMRHNQ AEGRRLLEQI HQLASSSDVP
MTTQVRIAAN IANGIKHAFK EFQASEILMG LHFHKDINKN FWGEFTRSLY NGLSRQIIIT
RITQPLNTIR RIQVAVPSRA EFEPGFYRWL ERLARMAGNL ECRIVFHGRR ESLQLITEFI
RNRFPSVRAE YEEMYHWKEL PDLATRVKAD QLFVIVTARK GTISYKSAME RLPEEVNRYF
KGKTLMIIFP DQYGNRMDDM TFAQPQHTEE RSAYEAVREW IHNKV
//
