ID I0WHQ9_9FLAO Unreviewed; 610 AA.
AC I0WHQ9;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=L-ornithine N(alpha)-acyltransferase {ECO:0000256|ARBA:ARBA00039866};
DE EC=2.3.2.30 {ECO:0000256|ARBA:ARBA00039058};
GN ORFNames=W5A_03244 {ECO:0000313|EMBL:EID75925.1};
OS Imtechella halotolerans K1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Imtechella.
OX NCBI_TaxID=946077 {ECO:0000313|EMBL:EID75925.1, ECO:0000313|Proteomes:UP000005938};
RN [1] {ECO:0000313|EMBL:EID75925.1, ECO:0000313|Proteomes:UP000005938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K1 {ECO:0000313|EMBL:EID75925.1,
RC ECO:0000313|Proteomes:UP000005938};
RX PubMed=22740661; DOI=10.1128/JB.00506-12;
RA Kumar S., Vikram S., Subramanian S., Raghava G.P., Pinnaka A.K.;
RT "Genome Sequence of the Halotolerant Bacterium Imtechella halotolerans
RT K1T.";
RL J. Bacteriol. 194:3731-3731(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3R)-hydroxyacyl-[ACP] + L-ornithine = a lyso-ornithine
CC lipid + H(+) + holo-[ACP]; Xref=Rhea:RHEA:20633, Rhea:RHEA-COMP:9685,
CC Rhea:RHEA-COMP:9945, ChEBI:CHEBI:15378, ChEBI:CHEBI:46911,
CC ChEBI:CHEBI:64479, ChEBI:CHEBI:78827, ChEBI:CHEBI:138482;
CC EC=2.3.2.30; Evidence={ECO:0000256|ARBA:ARBA00036203};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20634;
CC Evidence={ECO:0000256|ARBA:ARBA00036203};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. OlsB subfamily.
CC {ECO:0000256|ARBA:ARBA00038095}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EID75925.1}.
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DR EMBL; AJJU01000003; EID75925.1; -; Genomic_DNA.
DR RefSeq; WP_008237368.1; NZ_AJJU01000003.1.
DR AlphaFoldDB; I0WHQ9; -.
DR STRING; 946077.W5A_03244; -.
DR PATRIC; fig|946077.3.peg.656; -.
DR eggNOG; COG0204; Bacteria.
DR eggNOG; COG3176; Bacteria.
DR OrthoDB; 1113830at2; -.
DR Proteomes; UP000005938; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07986; LPLAT_ACT14924-like; 1.
DR InterPro; IPR045746; ACT14924-like_Acyltransf_dom.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR37323; GCN5-RELATED N-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR37323:SF1; L-ORNITHINE N(ALPHA)-ACYLTRANSFERASE; 1.
DR Pfam; PF13444; Acetyltransf_5; 1.
DR Pfam; PF19576; Acyltransf_2; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:EID75925.1};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Reference proteome {ECO:0000313|Proteomes:UP000005938};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EID75925.1}.
FT DOMAIN 81..203
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 610 AA; 70408 MW; 57B0074744F08C48 CRC64;
MGLVTAKEVA KAINLDKYGF VGTFIGWLLM KVLKISTLNK IYNRNKHLKE LDFLNAILDE
FEIQFEIPEE DLKRLPKDGA YITISNHPLG GIDGILLLKL LLEHRPDYKI IANFLLHRIE
PLAPYIMPVN PFEEHKDAQS SITGFMQSMR HLKEGKPLGV FPAGEVSTYK DGRLIVDRPW
EEAAMKLVKK ARVPVVPIYF HAKNSKLFYS LSKMNDTFRT AKLPSELLSQ KNRVIKVRIG
RPISVETQDE IDNIDEFCEF LRKKTYMLSN VYLKERKFVP LPTTIKIPKI PKAPKAIVEP
ICGEAMEKEV LKLRGGEAHL LTSKNYEVFL ATAQQIPSIL QEIGRLREIT FRAVGEGTNN
ATDLDMFDDY YHHLFLWDNE AKKVVGAYRM GLGSQIFAKY GIDGFYTQDL FRFEPELYKM
MSETIEMGRA FVINEYQQKP MPLFLLWKGI VHTTLRYPEH KYLLGGVSIS NQFSNFSKSL
MIEFMKSNYY DPYIAQYIKP KKEFKVKLKD ADKDFIFDET DADLNKFDRI IDEVEPGNLR
LPVLIKKYIK QNARVVAFNV DPLFNNSVDG LMYIRIADLP ESTVKPVMEE FQAELERKFM
NGVATDSEIK
//
