ID I0XN53_9LEPT Unreviewed; 461 AA.
AC I0XN53;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 28-JUN-2023, entry version 29.
DE SubName: Full=Metallo-beta-lactamase domain / RNA-metabolizing metallo-beta-lactamase multi-domain protein {ECO:0000313|EMBL:EIE00311.1};
GN ORFNames=LEP1GSC185_3321 {ECO:0000313|EMBL:EIE00311.1};
OS Leptospira licerasiae serovar Varillal str. VAR 010.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049972 {ECO:0000313|EMBL:EIE00311.1, ECO:0000313|Proteomes:UP000004889};
RN [1] {ECO:0000313|EMBL:EIE00311.1, ECO:0000313|Proteomes:UP000004889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VAR 010 {ECO:0000313|EMBL:EIE00311.1};
RX PubMed=23145189; DOI=10.1371/journal.pntd.0001853;
RA Ricaldi J.N., Fouts D.E., Selengut J.D., Harkins D.M., Patra K.P.,
RA Moreno A., Lehmann J.S., Purushe J., Sanka R., Torres M., Webster N.J.,
RA Vinetz J.M., Matthias M.A.;
RT "Whole Genome Analysis of Leptospira licerasiae Provides Insight into
RT Leptospiral Evolution and Pathogenicity.";
RL PLoS Negl. Trop. Dis. 6:E1853-E1853(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE00311.1}.
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DR EMBL; AHOO02000012; EIE00311.1; -; Genomic_DNA.
DR RefSeq; WP_008591663.1; NZ_AHOO02000012.1.
DR AlphaFoldDB; I0XN53; -.
DR PATRIC; fig|1049972.3.peg.3143; -.
DR OrthoDB; 9803916at2; -.
DR Proteomes; UP000004889; Unassembled WGS sequence.
DR CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
FT DOMAIN 21..241
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 254..374
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 461 AA; 52072 MW; 918B83F60DADDAA2 CRC64;
MENQNERLVS LQFLGGVGTV TGSKYLLKAF GKSIMIDCGL FQGEKKLRLL NWDSDQFFPT
EIDHILLTHG HLDHCGYLPR AVKKGFRGKI FGTKPTLDVS NIVLRDSAKL QEEDAELANS
GGYSKHKPAF PLYDSDDAEK TIKLFYAVEI GEWIDLEPNI KFRFRYNGHI LGASFIEFKI
GNKTLIFSGD IGRDEDPLLF PPEKPEEGDI ILIESTYGNR IHRGNPIKRL AQLIHEFSTT
KGTIVIPCFA VERIQAVMYL IWKLMKEGEI PNIPVYMDSP MGSKVLDLFD IYGSEWHKLR
GDELAELKDD IICITESSET KKIVSKRGPK IVIAGSGMAT GGRVLSYLEH SLGDPNSLVL
FVGYQARETR GNKLLRGDTE IKIRGKYHEV RCDVQNIDGL SAHADQTELI NWLSKIKNPP
KEVFIVHGEE DASRILGNRI RSVYGWETKI PERGEVFEFE V
//
