ID I0YPH7_COCSC Unreviewed; 686 AA.
AC I0YPH7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Not3-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=COCSUDRAFT_58005 {ECO:0000313|EMBL:EIE20296.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE20296.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE20296.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE20296.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005290}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005290}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family.
CC {ECO:0000256|ARBA:ARBA00007682, ECO:0000256|PIRNR:PIRNR005290}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE20296.1}.
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DR EMBL; AGSI01000016; EIE20296.1; -; Genomic_DNA.
DR RefSeq; XP_005644840.1; XM_005644783.1.
DR AlphaFoldDB; I0YPH7; -.
DR STRING; 574566.I0YPH7; -.
DR GeneID; 17038272; -.
DR KEGG; csl:COCSUDRAFT_58005; -.
DR eggNOG; KOG2150; Eukaryota.
DR OrthoDB; 10289at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0030015; C:CCR4-NOT core complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-UniRule.
DR GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.1020; CCR4-NOT complex subunit 2/3/5, C-terminal domain; 1.
DR InterPro; IPR038635; CCR4-NOT_su2/3/5_C_sf.
DR InterPro; IPR012270; CCR4-NOT_su3/5.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007282; NOT2/3/5_C.
DR InterPro; IPR007207; Not_N.
DR PANTHER; PTHR23326; CCR4 NOT-RELATED; 1.
DR PANTHER; PTHR23326:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; 1.
DR Pfam; PF04153; NOT2_3_5_C; 1.
DR Pfam; PF04065; Not3; 1.
DR PIRSF; PIRSF005290; NOT_su_3_5; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005290};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005290};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|PIRNR:PIRNR005290};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR005290};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR005290}.
FT DOMAIN 4..227
FT /note="CCR4-Not complex component Not N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04065"
FT DOMAIN 569..679
FT /note="NOT2/NOT3/NOT5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04153"
FT REGION 246..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 41..97
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 248..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..407
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..435
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 76603 MW; B4E4BB05EF2D1D87 CRC64;
MGANRKLQQE IDRTLKKVAE GIEVFDQIWE KVYDADNHPQ KEKYEGDLKK EIKKLQRFRD
QIKTWISGTD IKDKTDLVEA RKKVERQMER FKVCEKEMKV KAFSKEGLGQ ATKLDPKEKA
KNEMREWINE TVDKLTAENE TFDAEMESLA NNNKKKNKLP PRHSHLEESI VRHKAHVTRL
EQMLRLLDNE ALEPDDMTDI KEMVDDYMDR NQDSFDEFSD PDQAYEVILE QLDGLEATLP
VTMAVTHVKA KDPKEKEKEK EKEREREKQL ERERAAAQAA KQQLAAQAGI KLEETDPSPE
KPAALPRKAS EAGAGPKPPK EPVTPTGRTA IAVNTKADTP TAASNAPPTP VRVQTAFSPG
PTSPMASRQD HIAGSSRHTS LDTREDVATT PLAAPPPPPP PAAPSPASWA FPGDSDGFPQ
LGQAQLQQDQ QRRAAAQRGA QPAGALQTSL PDKAAQPAAM ATANQKLLFA NAVAGRPSEL
GGQPDDAQQV ALAGKDDGKL AAALLPPGQV GELLGGQGGR AAPAVLGPMA SPQDTLKLLT
ACSERCKPQL ADSQWQTVPP RLRPFPGGVP ASYPTEKAPM VQHPALFERL DTEALFFAFY
YQPGSYQQYL AARELKRQSW RYHKQHAAWF QRHEEPKTAT EEYEQGTYVY FDYNIVHDDQ
QVGWCYRLKQ DFMFKYDALE DELRID
//
