ID I0YPN0_COCSC Unreviewed; 3057 AA.
AC I0YPN0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=COCSUDRAFT_83549 {ECO:0000313|EMBL:EIE20349.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE20349.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE20349.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE20349.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE20349.1}.
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DR EMBL; AGSI01000016; EIE20349.1; -; Genomic_DNA.
DR RefSeq; XP_005644893.1; XM_005644836.1.
DR STRING; 574566.I0YPN0; -.
DR GeneID; 17038148; -.
DR KEGG; csl:COCSUDRAFT_83549; -.
DR eggNOG; KOG0939; Eukaryota.
DR OrthoDB; 325244at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR010309; E3_Ub_ligase_DUF908.
DR InterPro; IPR010314; E3_Ub_ligase_DUF913.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR11254; HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; 1.
DR PANTHER; PTHR11254:SF446; HECT-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF06012; DUF908; 1.
DR Pfam; PF06025; DUF913; 2.
DR SUPFAM; SSF46934; UBA-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264}.
FT DOMAIN 54..211
FT /note="DUF908"
FT /evidence="ECO:0000259|Pfam:PF06012"
FT DOMAIN 278..540
FT /note="DUF913"
FT /evidence="ECO:0000259|Pfam:PF06025"
FT DOMAIN 551..622
FT /note="DUF913"
FT /evidence="ECO:0000259|Pfam:PF06025"
FT REGION 325..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1028..1053
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1429..1465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1601..1622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1674..1779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1798..1832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2124..2147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2185..2368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2464..2506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2736..2785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2900..2989
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3008..3032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2662..2724
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1038..1053
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1691..1723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1752..1772
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1818..1832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2193..2248
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2272..2295
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2317..2331
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2338..2366
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2755..2785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2901..2919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3057 AA; 323787 MW; 58BA5CB8D72CFEDB CRC64;
MITGIVFQSD LSTSQSSFEE EMEHRRKKLA AIKCLSLGTT LNFQFYADAS DAGKAPADSS
EPSGLRVINL QHLDRYQESE HDILRQLVQR FAVPEKLRFS LLGRITVARK FGTLEGRRHL
ARLRLLSLHI LFQCNPSPEA VAEFYSQEPE FVSDLVCLLV GGAAIPEDLR ILALRVLAVQ
LLDRTHHTGV ITAISSGGQS GLLSMLMHRS IASVAAGAAG GAQPEYSVQF VDALLTLVGA
LSASTSGCSA LQEAGTLSAL MPMLKDTDPA HIGLVASAVR ILEAFMDFST SSASQFREMG
GLTDMIDRLK LEVGITAEPD QAVTPAAAAR PDDMQTDAPA PRAVAAPAGP KSGAAAPQPG
VLISYQRRVL LKALLRTIAL TSYAPGASAR PQEEDSAALY ACLRRIFERS SEFGGGLFAL
SASVMTDQMH HEPLTFTALE EAGLPEAFLN TIKAGVLPSG EAVCAVPSTL VALCLNEKGL
ERVKESKALD CFVPIFTTPT YLRALQFQGD TPSALGSNFD ELMRHVNSLR NDTVEMVLTI
FHDAKPADVT PADVDMSGSA AASSKAGSDR HANWHPHVAE CIMHSARLLE TMLANQSFSR
QFVEKGGLQL LLRLYTLKHL PPTFGSSSAA HAVMAAFRAC TQLHGALVTE KVAEALAEHL
RTTLLLAMSI GRSALQDVDA KRRDEYTRCV SSLEGVTSLA SAVSRSGMSM LNEVSKAGRF
AGLKTLVLDE PVPELALAVE NVTPASAIIA RVGDLERIVH LQIALAENRK AEMDAEGLLE
AASAEGVQKA APQEPAPEAE AASAVQNFAE LVDGLSMRQQ QRVLREAAMR ANQGLPMPSR
ALLLAAESER LAEDGDVVEP PAAGSPREAS GGHKNGKKKS GEDLALEVLT HFAATVRGFY
SSLTKSIHTP LRRREEGLAM TPAIRSTALH LGLVMKMNCE GDAEASSSSA GSLPPAKYKE
WSQWRARYLS AMVDDLGVVL FDNRRGTCHC LMLNYWVRCG GLQAFLAQFG TAAQFLWDVT
AAEAALGSAP ASQMEEAPSS KDARRKTEAE RKRVGRVKER AEMLLASMLA LLNQLSDSAR
ILNSPLAASL LVVPLNDEDQ ETNAAWSSAE NLVKSLKSAI LDAVLPVWGS PSLASCSPQN
TGAVTSILKH CTEAVTPPAS RSGARGAPPP DPAIVQQVVE MGFSEERVGH NSVELAMEWL
ISHPEELMEA APPAPQPQAD QVPVVAKAIN LAPAQALLKP KNEAPSTEQL VDGAVSVLEQ
VPTAAFSLAD LLKSHSAQQG CREDGAVIAR LLQRLHSGDS FAETVSGQPA VGLLAPAHLL
ALLCDDDPGM RRAGAKTALK GLGTGDVEPI PRWVDALLLV LDACTRIDWQ APEAPASAPE
LNSVNEPAAP EAEQACPLIC ILCYEHEMMM LMVVVVVVVV GMDVDAPGAP EQPAATTSAP
AAEEAQALEQ PSAPGPADTT AMPEPAPSVE DVFRKLPKHE GILSEEEEDR AVRVAMALLR
HLHAWGAVYQ EPKETPTEAA ALQLPDPPSS AQGVLLLLSC LTKRHSIALK VLAGRGPKLI
LELPLACFTP DLEPYISAIM RHILEDPVTL QAAMEAEIRS TLTKGRAPKP SGYPSVSQQS
DGSMPVKQFL QTCAAVINRE PTVFFDAVLG TCTIRENNGR PLVVLKKVKA DGAKLSDDKK
DGDAPSGGPP DSSTGGASRG SGASGPSAAT PDPQGNPASS SGGVGAGGGT PGGGPPGGGP
GGGGGGGGGG GKTPKDKDKE KEKEKDGKTP GRSGKKVPSN FVEVIDTLVD LVLRYEGPYS
ESKPKDPSTG AAAMDTDTPA AQPSSSEAPS ADVTLSADLD VKQIAAQVEQ AARAKSLEHR
QQEKNMLVQC IALKMLTDFT LMYNACVGVL LKRDAEGTRG RGSSPPSTPA APKLDSAQNL
LFRHLVFMPE PEVSMQPLGE QTSFFLQAVC IRSAEGRKRI ISEIVRTLSP SPDQKPPAAG
GMPSAEVLAT IPFKQKDGFP PPYKVKAFVE LAGSLLSAGA AKSQAGQPSG LSGEMLRCMR
SAGVINALIG ALKLIDMDHP NAVKSITSIL KPLEILTRAL PPSLLGAFSR QSRQPRLFDR
TTLGGVLAAG PSEPDVERAL AALEGPSSGD EPMRDAQEES AAAGPEAVAA AERLRQAFER
DQNQDGVDGL SRSVESVMEQ IIEHAYGEDG MEGFPESDSE GDGTDEDVIE SEEDDAMGEE
PMPDMTDEED EDLEGAEGPD DEDDDDDDDD DHHRHHHRHH HHDSADQSVY SDDESSSDES
GDEDHEVEVI FDDIEEDAMV GPLMGDDQLI MEHGGDEDGS TEDEDDMHDG GEEGDDHGHY
EDGDEDDDVD DDEDEDGEDG EDFGIDDLPA MEDHDFLLED DEDGLLAWPE EDGMMGDEMF
HPNPHPPRWV GIPRMNGTHN LARAGAAAQQ NAVEMMVNEL LNTGALGGVQ VDGRDQRFRY
RMRATQQPNG APSAAGLPGA TGAPRHRLLQ RPPAAPGARS AADEGRSANE MRIMRMNQPF
PGLFGAEDAA GAGEYWMITA DNGQRGFPGP RGIMLQAPNA GSLIDFSGDV LRTPGVMAGM
SNWSNDGQPP SALESTQLAG QLEQSLVETL RQHAAPEEAE EHQAGAPPTA AAVDPLQEAQ
TAIAQALERA AGGEQVEAGQ DMDRVLSTIQ RHREELEQAH ANMERNQQAL RQMDERLRNA
PPDLQALLNS SAQVRQAVNA LQEASRAAAA LVSPAAAPPA PPQAAAGNAA RSTPQAVAAG
VSGQTASEQQ SNETMVSPQD ANRAAANVAT SLESLRQSIR SVDAVPEDLR EAWERLILTY
GEQGAARQGE QMPATAQALT DPQVDIIRQS LRDRVGGRLR ENGSQAAAAQ FERFVAGFDP
RNIAQVPADM QAMINAIERP ASAQRAQQTA AQPQPEGEQT PAATAPGALP PPAPRRTRYQ
ARLRGTPPQD VAERDSSERL RTGLAAALAR PPQRRPASQP AAQGQPPAAL STAIGAELFS
SAMSAAMSGM TASAQPAPAQ PPPSPPPIIG ANMLSAALSG AAALSSSAAE SQPQPEQ
//
