ID I0YTR9_COCSC Unreviewed; 668 AA.
AC I0YTR9;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=E2F/DP family winged-helix DNA-binding domain-containing protein {ECO:0000259|SMART:SM01372};
GN ORFNames=COCSUDRAFT_42835 {ECO:0000313|EMBL:EIE21788.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE21788.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE21788.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE21788.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE21788.1}.
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DR EMBL; AGSI01000011; EIE21788.1; -; Genomic_DNA.
DR RefSeq; XP_005646332.1; XM_005646275.1.
DR AlphaFoldDB; I0YTR9; -.
DR STRING; 574566.I0YTR9; -.
DR GeneID; 17039773; -.
DR KEGG; csl:COCSUDRAFT_42835; -.
DR eggNOG; KOG2578; Eukaryota.
DR OrthoDB; 1761at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR015633; E2F.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR PANTHER; PTHR12081:SF7; TRANSCRIPTION FACTOR EFL-3; 1.
DR Pfam; PF02319; E2F_TDP; 2.
DR SMART; SM01372; E2F_TDP; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 243..310
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 367..449
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 71073 MW; 792FB15E2A0C83C0 CRC64;
MANDFSIPGD DILENSSQVP TRKRSMRPRC PRTLLEETYY VSPLDGQSMD EGDLSDESAE
DEEAAALLLE MGHFLDSAVD ARALSPAAQP AKAGGRKQGA SISFRCTSCH QPAVLRGEKR
PTFFCASCPS KGGAQKRAQR ALHGSSGRLI SVAEATELLA ARSGGIAPPK QQAQQQRVCP
PIFQGMGPER ERCMERLPSV PVQNRAADPD WVPSQLARAC SEGGEANQGR CKCGKRISAA
HPPCKSELML LCEKFQARFG GPQAAPSLIL LNEAAIELAV PRRRLYDIIN VLEAVEIVTR
TGKLAYEWRG LKHLPQLLDR LVADQLAGLP VEDRLRRTAA PAKNAAAAGS SEEGSGGDEA
APKERMPPTH SLWMLSRKFV RLLLTTQGPV PLAEAAVALI GADVAAARRA QAQITVERRL
YDIGSILSSV GLIEKTYLGK RQPAFSWRWP WRSSKPEVGA APASLKLPGS NGDSAHANSN
TSCGTLIDAS NTAPQGQNAA DDAQCLTPSS ATRAGDNAKR AWAAAVGGDP SAKRAKIEPA
PQPQPPFGAT RLCAAVTEHM AGHMLAHPLP QPMSLPGFAW GQGIPMPAVS MPPPGVSMPL
HLLAASYLPF PTSHADMAAM WNDPHFAAAL RSTAYLHLPM PSDARPPAAL PFPLPSQLSL
SAIGASQR
//
