ID I0Z388_COCSC Unreviewed; 624 AA.
AC I0Z388;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE SubName: Full=GIDA-domain-containing protein {ECO:0000313|EMBL:EIE25107.1};
DE Flags: Fragment;
GN ORFNames=COCSUDRAFT_1345 {ECO:0000313|EMBL:EIE25107.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE25107.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE25107.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE25107.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- FUNCTION: Involved in the 5-carboxymethylaminomethyl modification
CC (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
CC {ECO:0000256|ARBA:ARBA00002739}.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the MnmG family.
CC {ECO:0000256|ARBA:ARBA00007653}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE25107.1}.
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DR EMBL; AGSI01000004; EIE25107.1; -; Genomic_DNA.
DR RefSeq; XP_005649651.1; XM_005649594.1.
DR AlphaFoldDB; I0Z388; -.
DR STRING; 574566.I0Z388; -.
DR GeneID; 17043110; -.
DR KEGG; csl:COCSUDRAFT_1345; -.
DR eggNOG; KOG2311; Eukaryota.
DR OrthoDB; 5486689at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 1.10.150.570; GidA associated domain, C-terminal subdomain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR002218; MnmG-rel.
DR InterPro; IPR020595; MnmG-rel_CS.
DR InterPro; IPR026904; MnmG_C.
DR InterPro; IPR047001; MnmG_C_subdom.
DR InterPro; IPR044920; MnmG_C_subdom_sf.
DR InterPro; IPR040131; MnmG_N.
DR PANTHER; PTHR11806; GLUCOSE INHIBITED DIVISION PROTEIN A; 1.
DR PANTHER; PTHR11806:SF0; PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL; 1.
DR Pfam; PF01134; GIDA; 2.
DR Pfam; PF13932; GIDA_C; 1.
DR SMART; SM01228; GIDA_assoc_3; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS01281; GIDA_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264}.
FT DOMAIN 552..622
FT /note="tRNA uridine 5-carboxymethylaminomethyl modification
FT enzyme C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01228"
FT NON_TER 624
FT /evidence="ECO:0000313|EMBL:EIE25107.1"
SQ SEQUENCE 624 AA; 65914 MW; C9E2C002367CFA2A CRC64;
MSCNPSIGGL AKGTLVREVD ALDGLMARAA DEAGIQFRML NASKGPAVRG PRAQMDRSLY
KAAMQRLLSA QMGLQIHDGA VTDLLLQRGG SAGQQATVAG VLLASGEKVL CSSVVITTGT
FLRGTIHIGS QSRPAGRMPS NAAAEAAAGA RCADAKATNA ADETAARAAG SLAETLDAEG
FRLSRLKTGT PPRLDARTVD FTGMERQPSD AEPIPFSFLH MADMDWAPPA RQVECYGTRT
TAATEALVTE AMASGRGARF ASGLTVTEGG CREPRYCPSL ETKFARFPGR SHHVWLEPEG
LDSHVLYPNG LSNSLEPDDQ LHLLRTVPGL EGARMLQPAY AVEYDYIDPR ELLPSLESRR
VGGLYLAGQI NGTTGYEEAA AQGLLAGANA AIPGEPLEVG RAQGYTGVLV HDLVTLGTGE
PYRMLSARAE FRLSLRPDNA DARLTPAGIR LGIVGEERQA AFAQRSTEMA AADELLLRVR
LTCSGWKRAG FPMAGAGGWF TAADMLARPG VTLEQVADAA ENGEAEGAEE LRALARNGGM
RRSSTASAVY DCRYRPYTAK QAAEAAELAR GEALRLPPDL DYGAVQLSAE DREKLGAARP
ATIAAAQRIP GVTPAALLLL LQHV
//
