ID I0Z601_COCSC Unreviewed; 898 AA.
AC I0Z601;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Exostosin-domain-containing protein {ECO:0000313|EMBL:EIE26070.1};
GN ORFNames=COCSUDRAFT_12762 {ECO:0000313|EMBL:EIE26070.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE26070.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE26070.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE26070.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC {ECO:0000256|ARBA:ARBA00010271}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE26070.1}.
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DR EMBL; AGSI01000003; EIE26070.1; -; Genomic_DNA.
DR RefSeq; XP_005650614.1; XM_005650557.1.
DR AlphaFoldDB; I0Z601; -.
DR GeneID; 17044074; -.
DR KEGG; csl:COCSUDRAFT_12762; -.
DR eggNOG; KOG1021; Eukaryota.
DR OrthoDB; 306428at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR004263; Exostosin.
DR InterPro; IPR040911; Exostosin_GT47.
DR PANTHER; PTHR11062; EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED; 1.
DR PANTHER; PTHR11062:SF268; FAMILY PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR Pfam; PF03016; Exostosin; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022968}.
FT DOMAIN 184..217
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 57..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 188..198
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 207..216
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 898 AA; 100968 MW; 6192DB1FB64C7043 CRC64;
MSNSAAVLSR VLAVFGLSLL LGASLLLTTQ WAIASFRPTL VEIDNLKHKL SIARPKRAQD
HALHRQGLPR QTRGAGNNWH AAVEDVQPPE QWLENPTQQT YSQHSAFDGD LRRNRSISQP
SSTDLEVQHS QQGSHKGNDT AEAAPRTQAL SANETDRCRT VLGDWCQHAL RQHAVLPRKQ
PPSSNLSCHA DCNGVGNCNA ITGTCDCPAG WKGVGCLERD PRPCTDRYRR YASVLLAQQG
QILSYFGAST AGLLSGVCDD DIAACYCNGT NARLPSYTGT GPHSYPPARQ GRPMGLHCQP
NKGDDGKALH WGQHEPSKLF DPDTGWCEAA TPFTRCDCFL DGMGGDYCDQ PHEQTCINQC
SGRGVCYLGF CKCDPGWFGH DCANRVAGLP ASDGEIFSCP KTLVPEQCMS GCRVVGLGNA
GVNLTEKPWL REVLPAAEQL QERRRPLIYV YDLPAEFNSR MLQYRLNKRE CVWRLFKDNN
ESYINSWTYG IESAFHERLL QALSSEHRTL DPEEADFFFM PVYTSCFLHP VWGYVDHPWY
YGPTIDCRRD GDMQICQTGA NRVMQAMFML LEAQKWVEVN HPWWRRKGGR DHIWLITHDE
GSCWAPKEIR LSIILSHWGR KDVNHTSNSA FKPWDNYTQE VIHPEWWPEG YTHHIKGHAC
YDPIKDLIIP NLKHPAEFAN FSPLVGHPQP PRDILFLFRG DVGKHRLPHY SRGIRQRLFA
LAQEHDWAGR HAILIGDRDD VAGDYSELLT RSKFCLVAPG DGFSPRAEDA ILHGCVPVVV
MDEVDPVFSS ILDWSAFSLR IAEADIEQLP QILLAVPEAR LQAMQRSLRN VWQRFKWSSL
PIFRRIVRDI YNSNLNSVLD MSAEACCEDP AREDAFATVM QWLAHRSAAL GPAAMGTN
//
