ID I0Z6L9_COCSC Unreviewed; 4541 AA.
AC I0Z6L9;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Gamma heavy chain subunit of outer-arm dynein {ECO:0000313|EMBL:EIE26288.1};
DE Flags: Fragment;
GN ORFNames=COCSUDRAFT_12377 {ECO:0000313|EMBL:EIE26288.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE26288.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE26288.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE26288.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm, cytoskeleton, flagellum
CC axoneme {ECO:0000256|ARBA:ARBA00004611}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE26288.1}.
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DR EMBL; AGSI01000002; EIE26288.1; -; Genomic_DNA.
DR RefSeq; XP_005650832.1; XM_005650775.1.
DR STRING; 574566.I0Z6L9; -.
DR GeneID; 17044298; -.
DR KEGG; csl:COCSUDRAFT_12377; -.
DR eggNOG; KOG3595; Eukaryota.
DR OrthoDB; 312149at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46532:SF4; DYNEIN HEAVY CHAIN 8, AXONEMAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46532; MALE FERTILITY FACTOR KL5; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 2103..2264
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2444..2593
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2826..2966
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 3101..3128
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3316..3371
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3620..3647
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EIE26288.1"
SQ SEQUENCE 4541 AA; 506304 MW; B0FB81C4345A143D CRC64;
DDHDDLVFSQ LAEAYGVPVD AAEKAILQRR EAVSTFYEPE GPAALTWFYQ TPTGKPVASP
PQLFLGNPQA ESLANKAVYF VRINTKGVSA ESCEADIAVG EVPMGALESL RALMSELYLP
VLREGGSWGR SSDKQTHTFL KMATQLTSTL TEAVATMAAS VDLKEPDQAL LEGLDTKPAS
LGRAAADDSL VAHVADVLMS WCASVDEALT QQQTAQHEGS QAGPRAELEQ WRSRLAALTQ
LTERLRSREC RLAIGIAGAA RCKAHKAWRD AEAKLTDAVN EARDNLKYLR ALDASWEPIY
QQSSLAAVHN CLPAVLANIY TMHTISRYYA LPERLTAFLQ SVTQQLIDCC RGFLGAAGKL
WDQDKTALIA KLGAAVGLRD AYLDAYRLTK ILTNLFQTWP LFWFEANEAA VFGQMDLFAK
RCRKLIELFT IIHQFSELAK HTHIEGLQAI MRRFGEIVEE VRRKPYDLLD AQKNIFDRDF
LEFNVHINDL EIALSTSSVL QGFVHASFEG IKSTEAALRL LRQFRSVLQR DSLKADLDAM
YSVIFQRFAK DLEAVQGMYE RGKRRPMLPR GTPPVTGHIL WARQLLRRIE PPMAQFARNK
ELMAAKESRP IIQLYNRVAR ALVEYEIVWH ASWLKGVDSA LGGLSCTLIC QDPSSGRHHV
NFQRSLLELI REARSLGRLG IEVPEAARLA LTQEHKFRAY YDRLCHLLLE HERVVSSVPA
AALPLLEPQL AAMEARLRPG ATVLTWASMN IDGYLHFAHQ GLSQLEGLVT KVADVLHSRA
DSNLRAVQAT RLVDLPPERT FAADEFASHQ SGFTKRQTER LSIRNKEVER SVDEVIRLAE
HSPCGDAEGV ILPDSAKGAF RQHYSQRMHQ AVLATTGDSL RALQRRVSGP VCNGVPAALF
QVAVELSVPS VGLSPSPAAI QASIDTAAQQ VLHCSKALRV WAGGQQAAES YGDLISRDAD
ITQVVQALAG AVEASTAGVA AFLGGFDSFS FLWQRDIATE HAKFLTSNPK LEDFEGELKK
YLAVERAVAE ASPSYRAGTL MLDTSPLRAS LKSEVAAWKA AFARNLHRKG AEDLRVFEAY
LRETSAKLSD KVADLEDVRS VMLTIKEVNE REVDIDAHIA PIEDMYALLA RYEVKLPAEE
LDSVSDLRQG WKRLRRRAKD AGEELHRLQQ AGFQKKLAAD VGSFVADARS FRIEWEANGP
MLPGLDPMEA VDRLKKFQQP FEMRKRKWDS LASGEELFGL PVTLYPGLEN TERELSMLNR
LYLLYVTVIT TIRGFGELLW TDVVAQMDTM NDTVLAFQAQ AKKLPKAALR EWQAFNDCKR
TIDDFLEQLP LFKALASRAM RPRHWQEIMR ATGTELDLSE DVFKLGHLLG ANILARRDAV
EDLASAALKE EAIEAKLAAI ALDWGDMALT FQEYKSRGAV VLKPSETAEL VEKLEDAQMA
LGSMATNRFA VPFREQVTTW LGKLGLIEQW LAVQNLWMYV EAVFSGGDIV KQLPLEAKRF
QNIDKSFMKA RFLLETQNVL AVCVSSDMLR SLLPTLLEQL ELCQKSLSAY LETKRAEFPR
FYFVSDPTLL EILSLGSDPP SVVPHFQSGL FDSLSNVTFD KADKGRILEM YSQQGEKVEL
EQPVEAKGMV EGWLQRLVDG MQGTMKAIIK RAHRNVIEMK LQDFIFSHPA QVALLGLQFQ
WTADTQASAA LVAAKTDKTA MVKAARKADG LLREMVAITL KSDLSRIQRT NLETCITVHM
HQKETSEDLV RKKVRDPTDF EWLKQCRFYW RDDRDTVIIS ICDVDFEYSF EYLGVKERLV
ITPLTDVCYV TLSQALGICQ VWHFTGSQEL SHACTLAQDL GNTLGKYVVV FNCSDQMDYK
GMGKIYKGLA QSGLWGCFDE FNRIDLSVLS VCAQQARVYC VLSAIRERRK QFTFTDGSSV
SLDPRVGFFI TMNPGYAGRQ ELPENLKALF RGVTMMVPNR QIIMKVKLAA CGYQENEVLA
KKFHVLYGLC EQQLSKQPHY DFGLRNILSV LRTAGASKRA NPDKSEVFLM MRTLRDMNMS
KFVAEDVPLF TSLIEDLFPA QKADRAQFPD ISAALKKVVA ERGLQAHQSW LNKCIQLYET
YLVRHGIMLV GPSGSGKTTI MECLAAALTE LGTKTVLWRM NPKARTPAAC CCFVAQAVTA
PQMFGRMDAA TGDWTDGIFA VLWRRAAKNK NQNTWIVLDG PVDAIWIENL NTVLTLANGD
RILMTGQMKA FFEPENLNNA SPATVSRAGI IYVSDSELGW QPIVASWLQA SALFMLAMLL
QPCFDRYVDR MLDFIRTNLK PVMHNEAACQ VSTLLTLLEG SLAAGDPPAD PPSPAAAAAH
AERVFVFCLT WSLGGLLHER DRPAFDAELR RLAPADLMPP KGDEGDTMYE WMVREDGGGW
RHWRDRVPQW IYPSEAERPN FAQMLIPTLD SVRYEHLLHL VYSVGKASLL VGGPGTAKTS
IVNQFLLRFP PDEATSKTMT FSSLTTPAIF QTAVEGCVEK RQGRTYGPVG GKTMAIFVDD
LSMPAVNEWG DQVTNEIVRQ LLEQGGMYSL EKPIGDMRYI VDTRFVAAMN VPGGGKNDIP
NRLKRQFAIF YVPPPSPVAV NTIFGALVQA SPGRFDASRF STDVVDVASK LVPATLALWG
KVAAKLLPTP AKFHYLFNMR ELSKVFQGLL LADRSRFDRS VAAAAGSFGG DVTTPAGYLA
ALWVHECGRV FGDKMITKED GAWVDNAIRD LAKQHFPPEV AAQLKRPLHF VDFLREPVTD
PETGEVIDAH PSVYESVVGG LPDIRKRVEA LQRRFNEESR GQKLELVLFQ DALTHLMRIS
RLLAMERGNV LLVGVGGSGK QSLARLAAYI AGAYCFQITL TKTYNASNLF EDLKALYKIA
GVKGQPVAFI FTDAEVKEEG LLEYINQLLM TGEVAGLLPK EELDAILNDV RPVFKRECMG
VPDTADNLYA FFLGRVRDRL HVILCFSPVG NKFARRAQQF PGLINGCTID WFLPWPEEAL
TEVAGKYIDE FPMSCPDPVK ASLKSLMGSV HVGVTAACQE YYERFRHASK SQRHVYVTPK
SYMSFLDGFR TLYASKLAET RELAGSINNG LQKMDGAKVD VNRMKGELAV KNLELAAASQ
EAEKLLRDIS DSTAIAEKEK AKVAVILDQV SATAAEIAAV KDDAEKDLAA AKPALDAALS
ALNSITPKDI VALKALKNPP DIVKRIFDCV LLLRYLPVQK VAWQEVKGSQ VLVGNYDEAV
KMMGDTAFLS SLINFPKEAI TDETVELLRP YFRAPDFNFD SAKKASGNVA GLCNWAEAMC
TYHDVAKVVE PKIVALRGAE SELKVATKEK DEAVAELAIV QSKLDVMQAE FDAAMAQKQA
LEEDAAATER RMCAANALLG ALAGEEGRWT EQSKAFDDQI QRLTGDCAIA SSFVSYLGPF
NREFRELLLT RDLLAGCRKL NIPFTKDMKV SSFLADDAEV GEWTLQGLPT DELSVQNGIL
VARASRFPVL IDPQGQGRAW LLQREASKGL RVSHLPDKNF RADCLSNGKP LLIENIEEEL
DPILDPVLEK RFIRQARGLT LQLNDKEVEY NEGFRLYCTT RLPRPHYTPE LSANVTLVNF
TVTQAGLEDQ LLGKLILQEK QELEEQRLAL MEEVQSYRRR IKQLEDDLLF RLSNSQARYL
CPARCLLQIS NGNLLDDTEL IGVLAVTKAT AAQVNAKLAG ASEARRRIGE ACEEYRPVAH
RAQIIYFLIA QFSTVNCMYQ TSLAQFNQLY EVAIDTAERS AISSKRIHNI IDHLTYEIYL
YIQRGLFERH KIIFALLLAI SVLTSAGKIK PEEVDIFLKG GGALNINSVK KKPKEWIPDA
VWLGVVALGD MGAFRDIVEA VTRAEGQWRR WYDAEAPERA PVPEYGDRLS KFERMCIVRA
WREDRTLVAA ADVIADALGQ RFVDSVPLNM ERAWAESSPR VPLICLLSPG ADPTKLIEDL
AKRKKIRTMG VSMGQGQEII AHNLLTAARA DGQWLLLQNA HLGLAYLSEL EGVLSKTEGV
HENFRLWITA EPHAAFPIGL LQMGIKLTNE APVGIQAGLR ASYQWVNQDI LDAVNRHEWR
QLLFVMTFLH SVVQERRKFG PIGWNVPYEF NQSDLSACVQ FLQNHLLEME AKRASAPTWE
TVRYMVSAIQ YGGRITDEFD KLLMDTYAEK YFQQARGGAL LPNYVLHKDI KEGVSYTVPQ
GTEIEIYRKA IEEVPSQDNP ELFGLHPNAD LTFRTLQVQA AVQLVLETRP QGGSAAGGSS
REDAIDRLCE DLLSKAPAQF EREEVREKLR RLPGGPSQPL TVHLRQEIDR INTVIGLTTA
TLRNLRLAVA GTIALSAQLT ESLEALYNAR IPRDWLAKSW EASTLGSWFA GLLARHDQLS
RWLNSGRPKA YWLTGFFNPQ GFLTAVKQEV NRRHTGDKWA LDDVVLTSEV THPARLDADA
IKEAPAEGVF VYGLYLDGCA WSAKENWLID AEPKKLFNPL PVLYVTGVQA KDKKKSGVFE
APVYRVKKRT GLNYITSFPL RTDEPSSKWI LRGVALLCSV D
//
