GenomeNet

Database: UniProt
Entry: I0Z6Q1_COCSC
LinkDB: I0Z6Q1_COCSC
Original site: I0Z6Q1_COCSC 
ID   I0Z6Q1_COCSC            Unreviewed;       318 AA.
AC   I0Z6Q1;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   08-MAY-2019, entry version 27.
DE   RecName: Full=Arogenate dehydratase {ECO:0000256|RuleBase:RU363004};
DE            EC=4.2.1.91 {ECO:0000256|RuleBase:RU363004};
GN   ORFNames=COCSUDRAFT_12515 {ECO:0000313|EMBL:EIE26320.1};
OS   Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC   Eukaryota; Viridiplantae; Chlorophyta; Trebouxiophyceae;
OC   Elliptochloris clade; Coccomyxa.
OX   NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE26320.1, ECO:0000313|Proteomes:UP000007264};
RN   [1] {ECO:0000313|EMBL:EIE26320.1, ECO:0000313|Proteomes:UP000007264}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C-169 {ECO:0000313|EMBL:EIE26320.1,
RC   ECO:0000313|Proteomes:UP000007264};
RX   PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA   Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA   Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J.,
RA   Proschold T., Salamov A., Schmutz J., Weeks D., Yamada T.,
RA   Claverie J.M., Grigoriev I., Van Etten J., Lomsadze A., Borodovsky M.;
RT   "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT   reveals traits of cold adaptation.";
RL   Genome Biol. 13:R39-R39(2012).
CC   -!- FUNCTION: Converts the prephenate produced from the shikimate-
CC       chorismate pathway into phenylalanine.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + L-arogenate = CO2 + H2O + L-phenylalanine;
CC         Xref=Rhea:RHEA:12536, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:58095, ChEBI:CHEBI:58180;
CC         EC=4.2.1.91; Evidence={ECO:0000256|RuleBase:RU363004};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-
CC       phenylalanine from L-arogenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EIE26320.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AGSI01000002; EIE26320.1; -; Genomic_DNA.
DR   RefSeq; XP_005650864.1; XM_005650807.1.
DR   STRING; 248742.XP_005650864.1; -.
DR   GeneID; 17044330; -.
DR   KEGG; csl:COCSUDRAFT_12515; -.
DR   KO; K05359; -.
DR   OrthoDB; 1090069at2759; -.
DR   UniPathway; UPA00121; UER00344.
DR   Proteomes; UP000007264; Unassembled WGS sequence.
DR   GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR   GO; GO:0047769; F:arogenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Chloroplast {ECO:0000256|RuleBase:RU363004};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007264};
KW   Lyase {ECO:0000256|RuleBase:RU363004};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Plastid {ECO:0000256|RuleBase:RU363004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW   Transit peptide {ECO:0000256|RuleBase:RU363004}.
FT   DOMAIN       26    202       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      221    310       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   318 AA;  35041 MW;  DAC4BC17476AF9D0 CRC64;
     MRVYPNKVGL FGAPAQIHSP SPVQHRVAYQ GVPGAYSESA ARKACPDAEP LPCDQFEVAF
     QALTQWLADT AVLPIENSVG GSIHTVFDLL IKYRLHIVGE VSVDVRHCLM ALPGVRKKDL
     RRVQSHPQAL SQCDLYLSSM TGVVREAVSD TAGAAQTIAQ NNMRDVAAIA SERAAELYGM
     DILDRGIQDA RDNVTRFIVL SRDPLIALPD ESRTFKTSIT SVVFSVMEGP GQLFKALSVF
     ALRDLDMTKI ESRPMRSNPV QLANGTVGGR RFRYLFYVDF VGNLADDLPQ NALRHLQEVT
     DFMRVLGCYP MHVQASLP
//
DBGET integrated database retrieval system