ID I0Z9S7_COCSC Unreviewed; 523 AA.
AC I0Z9S7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN ORFNames=COCSUDRAFT_26706 {ECO:0000313|EMBL:EIE27396.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE27396.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE27396.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE27396.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: Amino-acid degradation; L-alanine degradation via transaminase
CC pathway; pyruvate from L-alanine: step 1/1.
CC {ECO:0000256|ARBA:ARBA00025708}.
CC -!- PATHWAY: Photosynthesis; C4 acid pathway.
CC {ECO:0000256|ARBA:ARBA00025709}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC aminotransferase family. Alanine aminotransferase subfamily.
CC {ECO:0000256|ARBA:ARBA00025785}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE27396.1}.
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DR EMBL; AGSI01000001; EIE27396.1; -; Genomic_DNA.
DR RefSeq; XP_005651940.1; XM_005651883.1.
DR AlphaFoldDB; I0Z9S7; -.
DR STRING; 574566.I0Z9S7; -.
DR GeneID; 17045411; -.
DR KEGG; csl:COCSUDRAFT_26706; -.
DR eggNOG; KOG0258; Eukaryota.
DR OrthoDB; 5472891at2759; -.
DR UniPathway; UPA00322; -.
DR UniPathway; UPA00528; UER00586.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00609; AAT_like; 1.
DR Gene3D; 1.10.287.1970; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR045088; ALAT1/2-like.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11751; ALANINE AMINOTRANSFERASE; 1.
DR PANTHER; PTHR11751:SF373; ALANINE AMINOTRANSFERASE-RELATED; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EIE27396.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EIE27396.1}.
FT DOMAIN 148..505
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
FT REGION 33..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 523 AA; 57427 MW; E4106903976B4877 CRC64;
MSLRRGLEQR SALWALCRSV SVAAGGPLTQ RTHGFASLPD PIGDDSPPQN SKNGKVLHPD
LLNENLVRAE YAVRGELYLR GEELRKQGKE IIFTNVGNPH VLGQKPLTFN RQVLSLIASP
ALLEHPEVGR LFPSDAIARA KQVLTYFPGG MGAYSDSRGA EGVRKEIAEF ISKRDGYPSN
PNNIFLTDGA SPAVRYILNA IIRSDKDGIL VPVPQYPLYS ASIQLYGGEL VGYNLKEETG
WSMDIADVKK SVDDARARGI AVRALVFINP GNPTGQCLSY QNLEDIIKFA HEENIVLMAD
EVYQTNIFQD ERPFVSCKKV MMDMGAPYSE QELVSFHTIS KGALGECGMR GGMLEATNIH
PDTIDQLYKI ASINLSPNTF GQAGLALMVN PPKEGDPSHE QHEAEAAGII ASMRRRARMM
TDGFNACEGI TCNYTEGAMY SFPRLNLPPK ALQAAKKAGK APDTWYCLKL LDATGVLTVP
GSGFGQEEGT FHLRTTILPQ EDKIKDVIAS FQKFHASFMD EYR
//
