ID   I1BHG3_RHIO9            Unreviewed;      1280 AA.
AC   I1BHG3;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Raptor N-terminal CASPase-like domain-containing protein {ECO:0000259|SMART:SM01302};
GN   ORFNames=RO3G_00347 {ECO:0000313|EMBL:EIE75643.1};
OS   Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL
OS   43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX   NCBI_TaxID=246409 {ECO:0000313|EMBL:EIE75643.1, ECO:0000313|Proteomes:UP000009138};
RN   [1] {ECO:0000313|EMBL:EIE75643.1, ECO:0000313|Proteomes:UP000009138}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880
RC   {ECO:0000313|Proteomes:UP000009138};
RX   PubMed=19578406; DOI=10.1371/journal.pgen.1000549;
RA   Ma L.-J., Ibrahim A.S., Skory C., Grabherr M.G., Burger G., Butler M.,
RA   Elias M., Idnurm A., Lang B.F., Sone T., Abe A., Calvo S.E.,
RA   Corrochano L.M., Engels R., Fu J., Hansberg W., Kim J.-M., Kodira C.D.,
RA   Koehrsen M.J., Liu B., Miranda-Saavedra D., O'Leary S.,
RA   Ortiz-Castellanos L., Poulter R., Rodriguez-Romero J., Ruiz-Herrera J.,
RA   Shen Y.-Q., Zeng Q., Galagan J., Birren B.W., Cuomo C.A., Wickes B.L.;
RT   "Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a
RT   whole-genome duplication.";
RL   PLoS Genet. 5:E1000549-E1000549(2009).
CC   -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC       {ECO:0000256|ARBA:ARBA00009257}.
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DR   EMBL; CH476732; EIE75643.1; -; Genomic_DNA.
DR   AlphaFoldDB; I1BHG3; -.
DR   STRING; 246409.I1BHG3; -.
DR   VEuPathDB; FungiDB:RO3G_00347; -.
DR   eggNOG; KOG1517; Eukaryota.
DR   InParanoid; I1BHG3; -.
DR   OMA; HHHPLWK; -.
DR   OrthoDB; 103066at2759; -.
DR   Proteomes; UP000009138; Unassembled WGS sequence.
DR   GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR004083; Raptor.
DR   InterPro; IPR029347; Raptor_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   Pfam; PF14538; Raptor_N; 1.
DR   Pfam; PF00400; WD40; 2.
DR   PRINTS; PR01547; YEAST176DUF.
DR   SMART; SM01302; Raptor_N; 1.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009138};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   DOMAIN          80..233
FT                   /note="Raptor N-terminal CASPase-like"
FT                   /evidence="ECO:0000259|SMART:SM01302"
FT   REPEAT          1148..1190
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1199..1226
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1280 AA;  143448 MW;  AE9FEE3663D4BD37 CRC64;
     MVSATIDNNE DAKSTSSTLV NGEETTRNNQ NAQMRHGFDE ELYEEDIIRF LYFSEKRHEA
     NSKSNTQVKN ALKDWRLRER IKTVSGLLVV CLNIGTDPPD IVKTNPCAKL ECWIDPFLLV
     PSKSLEAIGK NLHNQYETIN GRTRFKLSLD PSVEETKKIC CQMRRNAKEE RILFHYNGHG
     VPKPTTSGEI WVFNRNYTQY IPVSLFDLQS WLGSPVIYVW DCSAAGNIIN AFNRFAEQRD
     SEAVRLTQEQ HHPIVSWKDS IQLAACGPTE TLPMNPDLPA DVFTACLTTP IEMSLRWVVM
     RNPLLTSNIT MDMVLQLPGR ATERRTPLGE LNWIFTAVTD TIAWCVLQDQ PELFKRLFRQ
     DLMVASMFRN YLLAERIMRS YQCTPMSTPK LPETHDHPMW HAWDLAVDMC LFQLPALKAA
     ESGGPAYEYQ SSTFFSEQLT AFEVWLAEGA VNPKIPEQLP IVLQVLLSQV HRLRALILLS
     RFLDLGPWAV NAALSVGIFP YVLKLLQSPA AELKPVLVFI WARILAVDQS CQNDLLKDHG
     YAYFINILTP NNAMLSIPHV SEHRAMSAFI LSVFCTDFRT GQQACLRGNV ISACLAHVND
     PDPLLRQWIC LCLAQVWMNN SEAKSIAIAE NGHEKMTVLL NDSVPEVRAS AMYALGTFLS
     DPNKTEQIVN IEHNIAISAL CVMSDGSPMV RREFVIALSH IVHQAGSAKF LTAASQTIEE
     DQRISDKAML RGGVGATRQS EWRAALDGHF GSSSFDSVYA VLWKALLNLS VDPHPDVSKV
     ASIVVDHITA TLLNTPFIGE YASNLARDQQ VTSSTSAIIG QDLADDQDVP RSPTSSSFAR
     RPVKLARSVS FASTLRTIYN FGNVSYQDSP NGNIADGRPS KHAQTTHEEK VLPISSSFYD
     WSCEYFTEPQ MRAAEADEPG SVIYTKRKWR RSRNENILQE SNLTKGMAGS SRWDEQLSSM
     YNDTEASLLL FHQFEPHLVA ADSYNCLVVW DWKNGTPLSV IDNNNPPHSR ITDMKFLNEE
     DEALLLTGSD DGVVRLYKNY DQEQAVLISS WRALKDMEKS NSKQSGLVTD WHQARGYLFT
     GGDSKVIKVW DAHQELPVMD IPTQSLACVT SITTDQVNGN IVIAGFGDGS IGVYDRRLGP
     SESRVKKWDE HKAWITNIHL QREGTRELVS GGFEGDIKIW DIRETQSLKT IEAHTHSNMT
     SLAVHDHSYV VASAGADQVI KVWNMDGCRL STIRPSSGFL SQKATSTRAL SFHPNLMVMA
     ASGTDGYITL YNAHTTHTNM
//