ID I1C7T0_RHIO9 Unreviewed; 1046 AA.
AC I1C7T0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=RO3G_09220 {ECO:0000313|EMBL:EIE84510.1};
OS Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL
OS 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=246409 {ECO:0000313|EMBL:EIE84510.1, ECO:0000313|Proteomes:UP000009138};
RN [1] {ECO:0000313|EMBL:EIE84510.1, ECO:0000313|Proteomes:UP000009138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880
RC {ECO:0000313|Proteomes:UP000009138};
RX PubMed=19578406; DOI=10.1371/journal.pgen.1000549;
RA Ma L.-J., Ibrahim A.S., Skory C., Grabherr M.G., Burger G., Butler M.,
RA Elias M., Idnurm A., Lang B.F., Sone T., Abe A., Calvo S.E.,
RA Corrochano L.M., Engels R., Fu J., Hansberg W., Kim J.-M., Kodira C.D.,
RA Koehrsen M.J., Liu B., Miranda-Saavedra D., O'Leary S.,
RA Ortiz-Castellanos L., Poulter R., Rodriguez-Romero J., Ruiz-Herrera J.,
RA Shen Y.-Q., Zeng Q., Galagan J., Birren B.W., Cuomo C.A., Wickes B.L.;
RT "Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a
RT whole-genome duplication.";
RL PLoS Genet. 5:E1000549-E1000549(2009).
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DR EMBL; CH476738; EIE84510.1; -; Genomic_DNA.
DR AlphaFoldDB; I1C7T0; -.
DR STRING; 246409.I1C7T0; -.
DR VEuPathDB; FungiDB:RO3G_09220; -.
DR eggNOG; KOG1176; Eukaryota.
DR eggNOG; KOG1178; Eukaryota.
DR InParanoid; I1C7T0; -.
DR OMA; PLMFIFE; -.
DR OrthoDB; 2230730at2759; -.
DR Proteomes; UP000009138; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000009138};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 564..638
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1046 AA; 118671 MW; 41C4EA8D82A864A8 CRC64;
MPSAINSISD QSAIYYYKSF VNFINVQSKT YADRVFVRYY SNNTFKTLTY SEVDRITTNL
ACEWAEKKNG FEVVSYINEH NVDYMFTMFA LMKLRIIFLA ISPRNSEPAI VNLLEKTQSK
VIFATPKYES IAQSAAAKID GAKLTVIQPL DIEAMLNQPL NPRYKEILDF NFTEKDIDQP
ALIIHSSGST NFPKPIYLSN RYLLNASSFF QLYKEQYSHV HPMNEDDTML ACVPLFHLFG
LFCLGSIAFV GASTIFLKGL PPSQKEIDFA LRHNNCTVMA APPIILEQMI PYLQEHNDFS
AVQRLKFVLF GGAPFKREAG EWFQAHNVNV RNAYGSTEMN VTMCADLDPK SKNWNSLRPI
WNFSSESYIV LENTDDGLKH LYLTSNSPTL ALGISNRPDG GFNSNDLFRE DPEAPGCYIY
MGRRDDTLIM ENGEKTNPMP IESTIRQSPM VKQVAVLGHG YQCTSALIEI DLDYAINYGP
EEIISAVHEA VEDANKECSS HSTILPQMVK ILPFSKSLPS TDKGTVMRKK AEAMYKDVVE
KLYKDFLEGP NHTLDTDSSS WTPEQTESFL VKSAAQVLRL SESAFNDHSK SVFDLGLNSL
TAIQLRNAIA KAFSNVPQNF LFQHPTISSM REALLSENHV DPAQVIETRY QQTQELAQTY
VERAKDDFPV AKNEYEIEKK EKVVMLSGAT GSLGAFILRD LLKDASVKKV YCLVRGKESD
LYSRLVKAFE SRHLDSSLLE NDRVEALPMR LNEPYLGFTK ERYEQLKEEV TIVQHCAWLL
DFNMTIDHYD KECIAPFYNL LKFAYRQVNP MHVHFISSVS ASAGLGPEIE EKPLPFNSRV
AMPMGYAHSK FVCEILLNYL TKEKNFPCYV ERVGQVCGDS KNGVWNTSEQ YPLMFIAGGS
LMHKMPKLGT DVDWVSVDYA AAAIVAIMIR SSQLSADEDN SIYHIVNPRI ITWDDVLTAM
RSNGMKFDTV DPAEWVNTLS KDDTNPAFRL MSFYEDSFKN EFKMPIWQTK KTCDTAPILG
QSPTIDPILF KKYLSHWQSV GFYNPK
//
