ID I1CBX8_RHIO9 Unreviewed; 514 AA.
AC I1CBX8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
GN ORFNames=RO3G_10668 {ECO:0000313|EMBL:EIE85958.1};
OS Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL
OS 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=246409 {ECO:0000313|EMBL:EIE85958.1, ECO:0000313|Proteomes:UP000009138};
RN [1] {ECO:0000313|EMBL:EIE85958.1, ECO:0000313|Proteomes:UP000009138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880
RC {ECO:0000313|Proteomes:UP000009138};
RX PubMed=19578406; DOI=10.1371/journal.pgen.1000549;
RA Ma L.-J., Ibrahim A.S., Skory C., Grabherr M.G., Burger G., Butler M.,
RA Elias M., Idnurm A., Lang B.F., Sone T., Abe A., Calvo S.E.,
RA Corrochano L.M., Engels R., Fu J., Hansberg W., Kim J.-M., Kodira C.D.,
RA Koehrsen M.J., Liu B., Miranda-Saavedra D., O'Leary S.,
RA Ortiz-Castellanos L., Poulter R., Rodriguez-Romero J., Ruiz-Herrera J.,
RA Shen Y.-Q., Zeng Q., Galagan J., Birren B.W., Cuomo C.A., Wickes B.L.;
RT "Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a
RT whole-genome duplication.";
RL PLoS Genet. 5:E1000549-E1000549(2009).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|RuleBase:RU000461}.
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DR EMBL; CH476739; EIE85958.1; -; Genomic_DNA.
DR AlphaFoldDB; I1CBX8; -.
DR STRING; 246409.I1CBX8; -.
DR VEuPathDB; FungiDB:RO3G_10668; -.
DR eggNOG; KOG0157; Eukaryota.
DR InParanoid; I1CBX8; -.
DR OMA; NDYTHRF; -.
DR OrthoDB; 1828511at2759; -.
DR Proteomes; UP000009138; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR PANTHER; PTHR24305:SF166; CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000009138}.
SQ SEQUENCE 514 AA; 58998 MW; 00FFF2B138612398 CRC64;
MALEGLLPLF QKRSKSSYIV AAILLITVKQ IYSFFRVPTN LRHLPIVSFF AMVKSFLTSE
PPYSRFKRIT FPAIQKGNGF YVSKIPVGWT VYVANPVAAK QLLLKSDNFP KSHFGLDAIG
EKSTAVQFVG RDNIFLSNGE VWKKQRKIMN PVFHRSMPIK TVASLVPLLF SAIEEANGRI
MITPKMKDFT LDALGLTIFD FDFKALQGDP DHWTSIYRLV TRSIFDPISY VCSAMENFLT
YTYPTKRKGF NAVVKLNAKF DRLIEKKREE LQNGIFSNKP DNEKDLVTLM LEAGMQEDIS
ITNEELRHNM AALFLAGDDS ISNALSLCLY HLAKNKRVQQ KLREEIINIL GNGDMDIVPS
LEELKQMKYM NMVIKENLRL NMPVDVLLPR KTAEDIFLAG TFIPKDTIIV IDVGALHRDP
RSWKDPDEFV PERFEDDGEQ NSHEGLTWIP FGNGTRQCIG MNFSLMEQRL ILTMLLRKYE
VDLPKNSIHY DHIVYEHPTY ICPESLELIF TKRY
//
