ID I1E104_9GAMM Unreviewed; 713 AA.
AC I1E104;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:GAB59982.1};
GN ORFNames=RNAN_2995 {ECO:0000313|EMBL:GAB59982.1};
OS Rheinheimera nanhaiensis E407-8.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Rheinheimera.
OX NCBI_TaxID=562729 {ECO:0000313|EMBL:GAB59982.1, ECO:0000313|Proteomes:UP000004374};
RN [1] {ECO:0000313|EMBL:GAB59982.1, ECO:0000313|Proteomes:UP000004374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E407-8 {ECO:0000313|EMBL:GAB59982.1,
RC ECO:0000313|Proteomes:UP000004374};
RX PubMed=23209246; DOI=10.1128/JB.01922-12;
RA Zhang X.-Y., Zhang Y.-J., Qin Q.-L., Xie B.-B., Chen X.-L., Zhou B.-C.,
RA Zhang Y.-Z.;
RT "Genome Sequence of the Protease-Producing Bacterium Rheinheimera
RT nanhaiensis E407-8T, Isolated from Deep-Sea Sediment of the South China
RT Sea.";
RL J. Bacteriol. 194:7001-7002(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB59982.1}.
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DR EMBL; BAFK01000019; GAB59982.1; -; Genomic_DNA.
DR AlphaFoldDB; I1E104; -.
DR STRING; 562729.RNAN_2995; -.
DR Proteomes; UP000004374; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004374};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 183..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..127
FT /note="DUF4131"
FT /evidence="ECO:0000259|Pfam:PF13567"
FT DOMAIN 163..431
FT /note="ComEC/Rec2-related protein"
FT /evidence="ECO:0000259|Pfam:PF03772"
FT DOMAIN 462..533
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
SQ SEQUENCE 713 AA; 79644 MW; C93118D1DA4459DD CRC64;
MLLWWRCAFL AGMLAFLISW AWQYHSYLQA QQQLFSQQAP LTGFIVGTVQ QHAEYSQFKL
QLDSGAGRGY QLNLNWSYPP QALKSGQHWQ LSARLRPVAG VANPAGPNRE AMALVSGVLA
QGSVTDAAEP VLLGEYSSLR QRILAQVTEA TQALSSAPLL LALTLGERQF TDQLWLGLQQ
SGLAHLVAIS GLHIGLVFGW SLLVFRLLPL PLSLLRWQRP LSLLGALAAA LLYAWLAGFA
IPTVRAAVAL ALLVLSLLLR RSLSYSHYWL LLCALLLLAQ PFWALSKSFW LSILAVAVIF
FLLWLQSAHA SNWRQRLWFL LRFHLNLTVF MTLLSLLMFG GSATLSLLSN LLFVPWCSLL
AIPLLLLCLL AELSGIPGRQ WLWLACDGVF SPLLWYLNWC ANMPAWWAVP DLPIAVVVVL
ALLLSALYLQ QKRWLYSLVV LSALPLLLVF SRQAPWQLHL IDVGQGLAVL LQHNERGLLY
DAGPRYASHS ATAAQVLPYL RSQGIKQLDY LMLSHDDSDH TGDWALLKRH YPKLQVFSDI
KHSDINATCQ QLPAQYGAAR LTMLDTGGQH SSKNDRSCVL LIELYQWRIL LPGDIGAGVE
RQLLARYPTL RAEVLVLSHH GSNSSSDYAF LHQLAPIWAL NSASLYNRHQ HPAYPVRQRL
AQLGIPLVNT AQSGAIRLTI TEPMLQLEQY RAQRIPYWLQ KPVGNAETLA ATR
//
