ID I1GQL3_BRADI Unreviewed; 418 AA.
AC I1GQL3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN Name=100822930 {ECO:0000313|EnsemblPlants:KQK14341};
GN ORFNames=BRADI_1g15560v3 {ECO:0000313|EMBL:KQK14341.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQK14341};
RN [1] {ECO:0000313|EMBL:KQK14341.1, ECO:0000313|EnsemblPlants:KQK14341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK14341.1,
RC ECO:0000313|EnsemblPlants:KQK14341};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK14341.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK14341.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK14341}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK14341};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50A family.
CC {ECO:0000256|ARBA:ARBA00009989}.
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DR EMBL; CM000880; KQK14341.1; -; Genomic_DNA.
DR RefSeq; XP_003562341.1; XM_003562293.3.
DR AlphaFoldDB; I1GQL3; -.
DR STRING; 15368.I1GQL3; -.
DR EnsemblPlants; KQK14341; KQK14341; BRADI_1g15560v3.
DR GeneID; 100822930; -.
DR Gramene; KQK14341; KQK14341; BRADI_1g15560v3.
DR KEGG; bdi:100822930; -.
DR eggNOG; ENOG502QT40; Eukaryota.
DR HOGENOM; CLU_025778_1_1_1; -.
DR InParanoid; I1GQL3; -.
DR OMA; EYGHFWA; -.
DR OrthoDB; 3675515at2759; -.
DR Proteomes; UP000008810; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00989; PDZ_metalloprotease; 1.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 171..238
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 43550 MW; ABB8D4E4EDDC2DAA CRC64;
MITTAHISNP PSPCRPFHSH SPSSAAPLPL IRRHRHSKPF STAAASPSDL LASVESVASA
ASVLASIVLV HESGHFVAAT SRGIHVSQFS VGFGPALARF RLGPVEYALR AIPLGGYVGF
PDDDPDSGFA PDDPDLLRNR PVPDRLLVVS AGVIANLIFA FLIVYTQALT VGVPVQALLT
GVLVPDVISG SAAARAGLLP GDVILAVPGA APDPSVPALV DLIKASPNKK VLVTVSRTGP
GASDRQSLDL TIVPDTSADG TGRIGVQLSP NFRVTRVHPR NLSEATVLAV REYTALGGTV
LEGLKQTFLN FSQTAEKVSG PVAIIAVGAE VARSSADGLF QFAAVINLNL AAINLLPLPA
LDGGTLALIL LEAARGGQKI PREIEQRIMS SGILLVLMVG IFLIVRDTLN LDFIKENL
//
