ID I1GUX4_BRADI Unreviewed; 522 AA.
AC I1GUX4;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100831296 {ECO:0000313|EnsemblPlants:KQK16498};
GN ORFNames=BRADI_1g29040v3 {ECO:0000313|EMBL:KQK16498.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK16498.1};
RN [1] {ECO:0000313|EMBL:KQK16498.1, ECO:0000313|EnsemblPlants:KQK16498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK16498.1,
RC ECO:0000313|EnsemblPlants:KQK16498};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK16498.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK16498.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK16498}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK16498};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
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DR EMBL; CM000880; KQK16498.1; -; Genomic_DNA.
DR RefSeq; XP_003560270.1; XM_003560222.3.
DR AlphaFoldDB; I1GUX4; -.
DR STRING; 15368.I1GUX4; -.
DR EnsemblPlants; KQK16498; KQK16498; BRADI_1g29040v3.
DR GeneID; 100831296; -.
DR Gramene; KQK16498; KQK16498; BRADI_1g29040v3.
DR KEGG; bdi:100831296; -.
DR eggNOG; ENOG502QSTI; Eukaryota.
DR HOGENOM; CLU_018563_0_0_1; -.
DR InParanoid; I1GUX4; -.
DR OMA; IIGMSKV; -.
DR OrthoDB; 241511at2759; -.
DR Proteomes; UP000008810; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR004324; FBT.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00788; fbt; 1.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF12; FOLATE-BIOPTERIN TRANSPORTER 9, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF03092; BT1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 522 AA; 56357 MW; 997CBA5FA544319A CRC64;
MLCLTPCAPC PHRPNARAGT GAGDNAHRVT LCRLRTLGAV GRLRLVKFQS CAAAAPAPPA
GRPVKPFPPV PARTTAERWG SLREMRRVWW VCGVGYWVQG FRCFPWLALN FHLTRGLGLN
PAALQLVQNA GNLPLVAKPL FGVLSDAVYI GRAHRLPYIS IGVLLQLVAW GTLAIMPVTG
DTFPTQMVCI LIGNLGASVT EVVSDAVVTE FSRTQKTGVL QSYAFIGLAA GSLLGNLSGG
YVLLRTQEPK TMFTAFSILL GLQLALSVST KETLPSSHEN SKNLIRSSLA ANFRKQFSNL
LTAIHEERIF YPLAWIMTSF AVVPILSGTM FCFQTQYLKL DSSIIGLSKV MGQVMVLSLT
VLYNRHLKRI PLRQLVSGVQ IMYALAVLSE LILVKQVNLM LGIPNEIYVL CFSALAEAIA
QFKVLPFSVL LSSLCPPGCE GSLFAFFTSG LVFSAILSGV YGVGLATLIG LSAGDYSKLP
LGILLQTLAA LLPLGWISLV PENWTADDKV VKQALTSDRA QT
//
