ID I1H1Y3_BRADI Unreviewed; 352 AA.
AC I1H1Y3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=WAT1-related protein {ECO:0000256|RuleBase:RU363077};
GN Name=100842979 {ECO:0000313|EnsemblPlants:KQK20015};
GN ORFNames=BRADI_1g51910v3 {ECO:0000313|EMBL:KQK20015.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK20015.1};
RN [1] {ECO:0000313|EMBL:KQK20015.1, ECO:0000313|EnsemblPlants:KQK20015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK20015.1,
RC ECO:0000313|EnsemblPlants:KQK20015};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK20015.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK20015.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK20015}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK20015};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU363077}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU363077}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000256|ARBA:ARBA00007635, ECO:0000256|RuleBase:RU363077}.
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DR EMBL; CM000880; KQK20015.1; -; Genomic_DNA.
DR RefSeq; XP_003557257.1; XM_003557209.3.
DR AlphaFoldDB; I1H1Y3; -.
DR EnsemblPlants; KQK20015; KQK20015; BRADI_1g51910v3.
DR GeneID; 100842979; -.
DR Gramene; KQK20015; KQK20015; BRADI_1g51910v3.
DR KEGG; bdi:100842979; -.
DR eggNOG; ENOG502QWIP; Eukaryota.
DR HOGENOM; CLU_025359_1_0_1; -.
DR InParanoid; I1H1Y3; -.
DR OMA; HAGKKSW; -.
DR OrthoDB; 374071at2759; -.
DR Proteomes; UP000008810; Chromosome 1.
DR ExpressionAtlas; I1H1Y3; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; WAT1-RELATED PROTEIN; 1.
DR PANTHER; PTHR31218:SF250; WAT1-RELATED PROTEIN; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU363077};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transmembrane {ECO:0000256|RuleBase:RU363077};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363077}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 77..99
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 185..204
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 216..238
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 253..274
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 281..300
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 306..325
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT DOMAIN 14..156
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 187..325
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 352 AA; 38465 MW; E32A013673C42461 CRC64;
MFRSTMRGGI DEWKPVIAML VFDLISAVTT ALIKKALAEG LDRLVLVTLR QLVATAFLSP
IAFFKERGKR PKLTLEILVY LFFSAALGAA LSQYTFFYGL QYTTATFAIT FTNLAPVLTF
LIAVLLRVES LNMKNKAGAA KIAGTLMSFA GVMLLTLYKG VPLTHQAVPL GQHAAAEAES
GKKSWTLGTI ALLANGLCFS FWLLLQSKLT KKYPALYSST AYMFLISSLQ GGCVTGAIQR
RASVWALTKT VEIVTVLYTG ILGSGVGYVL MTWCVEKRGP VFTSSFIPII QIMVAIIDFF
FLHENIYLGS VLGSILMILG LYILLWGKSR DASVTAASAE EDEEDKEKQV KS
//
