ID I1HCI8_BRADI Unreviewed; 666 AA.
AC I1HCI8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE RecName: Full=Bicarbonate transporter-like transmembrane domain-containing protein {ECO:0000259|Pfam:PF00955};
GN ORFNames=BRADI_2g04690v3 {ECO:0000313|EMBL:KQK02966.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK02966.1};
RN [1] {ECO:0000313|EMBL:KQK02966.1, ECO:0000313|EnsemblPlants:KQK02966}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK02966.1,
RC ECO:0000313|EnsemblPlants:KQK02966};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK02966.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK02966.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK02966}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK02966};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31.3) family.
CC {ECO:0000256|ARBA:ARBA00006262}.
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DR EMBL; CM000881; KQK02966.1; -; Genomic_DNA.
DR AlphaFoldDB; I1HCI8; -.
DR STRING; 15368.I1HCI8; -.
DR EnsemblPlants; KQK02966; KQK02966; BRADI_2g04690v3.
DR Gramene; KQK02966; KQK02966; BRADI_2g04690v3.
DR InParanoid; I1HCI8; -.
DR Proteomes; UP000008810; Chromosome 2.
DR ExpressionAtlas; I1HCI8; baseline.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR GO; GO:0050801; P:monoatomic ion homeostasis; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF40; BORON TRANSPORTER 4-RELATED; 1.
DR Pfam; PF00955; HCO3_cotransp; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..180
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT DOMAIN 205..376
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT DOMAIN 457..547
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 642..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..657
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 74439 MW; CE541043FE89376E CRC64;
MDLLRNPFKG VVADVKGRAS WYKDDWVAGL RAGFRILAPT MYIFFASALP VIAFGEQLSR
ETNGMLSTVE TLASTAICGV IHSILGGQPL LIVGVAEPTI IMYTYLYNFA KEEAGLGEQL
YLAWAGWVCI WTAIMLFFLA MFNASNVISR FTRVAGELFG MLITVLFLQQ AIKGIVSEFS
LPKAAEIVDR SSLIYDFQWI YVNGLLGVIF SIGLLYTALK SRRARSWLYG IGCLRSFIAD
YGVPLMVIVW TALSYTLPSK VPSGVPRRLF SPLPWESSSL GHWTVAKDLF SVPPAFIFAA
IVPALMVAGL YFFDHSVASQ LAQQKEFNLK KPSAYHYDIL VLGFMVLLCG LIGIPPSNGV
LPQSPMHTRS LAVLKGQLMR NKMLQTAKEG MTNRASSLEI YGKMQEVFIQ MDREKNTDSV
DKELKSLKDA VLREGDEEGK LAGEFDPRKH IEAHLPVRVN EQRLSNLLQS LLVGGCVGAM
PVIKMIPTSV LWGYFAYMAI DSLPGNQFWE RIKLLFIGST RRYKVLEGPH ASFVESVPSK
TISVFTIFQL VYLLICFGTT WIPIAGILFP VPFFLMILIR QHLLPKFFDP NHLRELDAAE
YEELEGVQNE HTLEEDGSIS GSCDSRNDAE ILDELTTNRG ELKHRSVSHR EERHLQVHSN
AVQPSV
//
