ID I1HDI7_BRADI Unreviewed; 715 AA.
AC I1HDI7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100821912 {ECO:0000313|EnsemblPlants:KQK03409};
GN ORFNames=BRADI_2g07700v3 {ECO:0000313|EMBL:KQK03409.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQK03409};
RN [1] {ECO:0000313|EMBL:KQK03409.1, ECO:0000313|EnsemblPlants:KQK03409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK03409.1,
RC ECO:0000313|EnsemblPlants:KQK03409};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK03409.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK03409.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK03409}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK03409};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
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DR EMBL; CM000881; KQK03409.1; -; Genomic_DNA.
DR RefSeq; XP_003565953.1; XM_003565905.3.
DR AlphaFoldDB; I1HDI7; -.
DR STRING; 15368.I1HDI7; -.
DR EnsemblPlants; KQK03409; KQK03409; BRADI_2g07700v3.
DR GeneID; 100821912; -.
DR Gramene; KQK03409; KQK03409; BRADI_2g07700v3.
DR KEGG; bdi:100821912; -.
DR eggNOG; KOG1087; Eukaryota.
DR InParanoid; I1HDI7; -.
DR OMA; NGQIANH; -.
DR OrthoDB; 472902at2759; -.
DR Proteomes; UP000008810; Chromosome 2.
DR ExpressionAtlas; I1HDI7; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd14231; GAT_GGA-like_plant; 1.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898:SF7; OS01G0229200 PROTEIN; 1.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 9..138
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 174..262
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 141..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 77668 MW; 10163BE11159791F CRC64;
MAGSMVDRAT SDMLIGPDWA KNMEICDICN RDPGQSKDVV KALRKRIVHK NPKVQLLALT
LLETAIKNCG DIFQMHVAER DVLHEMVKMV KKKSDPRVKE KILVLIDTWQ EALGGPRARY
PQYYAAYHEL VRAGAQFPKR TERPAPLFNG QSQAANSMRS PDQRDEAESS AGNDFPALNT
TEIQNARGIM DVLAEMLNAL DPGNREGLRQ EVIVELVDQC RTYKQRVVQL VNTASDEELL
SQGLALNDDL QRVLAKHDAI AAGIAVRVEK KPKSLQALVD TEDSANQDSK KEQALVDIDD
PTSQDSKTEP NQSTSDQSPF EQLALPAPPM SNGSATHPPK PDSGIDLLSW DDTPSTAENS
LALVPVTDPL ADSTSNQNAL AIVDIFSQTS TATSSAKPLD PFGLNSSPAL QGSQPYNIPT
QQPLQSQQPP QQAALYPNGG AVNPGTSYDH ASQFNHTNSG WNGQAANHAT PPPQQMNYDD
QSGSLPPPPW EAQSVPSNEM SNGQLGGMQS LPTSQPGSVQ PLQPQNNHMG GLQTQPMYNN
QPGAMLPQTM QSSQTIGAQM QPGYGNQFGH QPQHSMPMPG MQFAGMQHSP MPGVQQPAMM
YGQQMPGTQF GGMPHQQMYG GQMAAAAYAA YGYMQQPGAQ YYNQGRPYGY PGTNDLSQNM
YGLSMQDSSH MGMNSSYQTT PSSSSMGQPI RPSRPEDKLF GDLLSIAKTK QNRAS
//
