ID I1HKJ9_BRADI Unreviewed; 420 AA.
AC I1HKJ9;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=tRNA (guanine(26)-N(2))-dimethyltransferase {ECO:0008006|Google:ProtNLM};
GN Name=100833677 {ECO:0000313|EnsemblPlants:KQK06858};
GN ORFNames=BRADI_2g30590v3 {ECO:0000313|EMBL:KQK06858.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK06858.1};
RN [1] {ECO:0000313|EMBL:KQK06858.1, ECO:0000313|EnsemblPlants:KQK06858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK06858.1,
RC ECO:0000313|EnsemblPlants:KQK06858};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK06858.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK06858.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK06858}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK06858};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Trm1 family. {ECO:0000256|PROSITE-ProRule:PRU00958}.
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DR EMBL; CM000881; KQK06858.1; -; Genomic_DNA.
DR RefSeq; XP_010231531.1; XM_010233229.2.
DR AlphaFoldDB; I1HKJ9; -.
DR STRING; 15368.I1HKJ9; -.
DR EnsemblPlants; KQK06858; KQK06858; BRADI_2g30590v3.
DR GeneID; 100833677; -.
DR Gramene; KQK06858; KQK06858; BRADI_2g30590v3.
DR KEGG; bdi:100833677; -.
DR eggNOG; KOG1253; Eukaryota.
DR HOGENOM; CLU_010862_5_1_1; -.
DR InParanoid; I1HKJ9; -.
DR OMA; DHYFRAF; -.
DR OrthoDB; 297945at2759; -.
DR Proteomes; UP000008810; Chromosome 2.
DR ExpressionAtlas; I1HKJ9; differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0002940; P:tRNA N2-guanine methylation; IBA:GO_Central.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.30.56.70; N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002905; Trm1.
DR InterPro; IPR042296; tRNA_met_Trm1_C.
DR PANTHER; PTHR10631; N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10631:SF9; TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE; 1.
DR Pfam; PF02005; TRM; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51626; SAM_MT_TRM1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00958};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00958};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; tRNA processing {ECO:0000256|PROSITE-ProRule:PRU00958};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555, ECO:0000256|PROSITE-
KW ProRule:PRU00958}.
FT REGION 14..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 420 AA; 46188 MW; EC9A1BAB845A2CED CRC64;
MASAAAVSFH QTLPPPLQHR RLGPTPPRCT HSERGVSFDP GSAFYRSESA PGRDLAVLAA
TIHRRRRLDP SGPFLCLDAM CGCGIRALRY LAQAGADFVW ANDASDALRP VVVGNLSRFE
PEPLDGQRRW VVSHLDATRL LAERYLRREY FDVIDVDSFG SEAEYIRAAF LALKIGGLLY
LTSTDWRSAR GYGGKCSLSS YGAYVRPVPY PNEIGLRMLL GGAAREAAML GFHITPVFSY
YAYHGPIFRA MIQLRHGKED GISNYGFICH CKSCGQTQTF GFHELGQISC RCADRTDATS
ITVVGPLWTG PLHDASSITE MLNLAVEWGW AYTTGNGVTL EKLLVTMIDE SDLRLPPGYI
RLDEIASRAK VNSPPLGTLI NSLQKEGYAA CRSHIGANAI KTNCPITSCI EVAREIRNLR
//
