ID I1HM12_BRADI Unreviewed; 394 AA.
AC I1HM12;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Ribosome biogenesis protein NOP53 {ECO:0000256|ARBA:ARBA00018339, ECO:0000256|PIRNR:PIRNR017302};
GN Name=100834313 {ECO:0000313|EnsemblPlants:KQK07592};
GN ORFNames=BRADI_2g36460v3 {ECO:0000313|EMBL:KQK07592.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQK07592};
RN [1] {ECO:0000313|EMBL:KQK07592.1, ECO:0000313|EnsemblPlants:KQK07592}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK07592.1,
RC ECO:0000313|EnsemblPlants:KQK07592};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK07592.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK07592.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK07592}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK07592};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: May play a role in ribosome biogenesis.
CC {ECO:0000256|PIRNR:PIRNR017302}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|PIRNR:PIRNR017302}. Nucleus, nucleoplasm
CC {ECO:0000256|PIRNR:PIRNR017302}.
CC -!- SIMILARITY: Belongs to the NOP53 family.
CC {ECO:0000256|ARBA:ARBA00008838, ECO:0000256|PIRNR:PIRNR017302}.
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DR EMBL; CM000881; KQK07592.1; -; Genomic_DNA.
DR RefSeq; XP_003568961.1; XM_003568913.3.
DR AlphaFoldDB; I1HM12; -.
DR STRING; 15368.I1HM12; -.
DR EnsemblPlants; KQK07592; KQK07592; BRADI_2g36460v3.
DR GeneID; 100834313; -.
DR Gramene; KQK07592; KQK07592; BRADI_2g36460v3.
DR KEGG; bdi:100834313; -.
DR eggNOG; KOG2823; Eukaryota.
DR HOGENOM; CLU_048046_1_0_1; -.
DR InParanoid; I1HM12; -.
DR OMA; TEKWTHK; -.
DR OrthoDB; 2912665at2759; -.
DR Proteomes; UP000008810; Chromosome 2.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008097; F:5S rRNA binding; IBA:GO_Central.
DR GO; GO:0000460; P:maturation of 5.8S rRNA; IEA:EnsemblPlants.
DR GO; GO:0051781; P:positive regulation of cell division; IEA:EnsemblPlants.
DR GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:EnsemblPlants.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR InterPro; IPR011687; Nop53/GLTSCR2.
DR PANTHER; PTHR14211; GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2; 1.
DR PANTHER; PTHR14211:SF7; RIBOSOME BIOGENESIS PROTEIN NOP53; 1.
DR Pfam; PF07767; Nop53; 1.
DR PIRSF; PIRSF017302; Gltscr2; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017302};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|PIRNR:PIRNR017302}.
FT REGION 59..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 44355 MW; EAAB58C679E67A01 CRC64;
MGKAAKGSRK GKKAWRANIR TDDIDEFFEK QTRDAHAGAA AIPSLPSDSL FFVDKPASAS
TSSAAVVSEP TSKDIPVKRK IEKNREKVLY HESILKRNPY VQTIPSSLVS KKDRKKLKKK
AKKEELQESR EDKVVPMEDD SAEKILDIWG GDAGFAKSKK GMQRLKKNRS TTSVFPAVEV
EPPGCSFNPD KEDHQDSLAQ AVANEMTKIY TKELGPKPVP LTVIGEAVTE EDKFFLDAAD
DGDAAEGNGD QDADDVAGQR KTKTKRVTRV ELNKRARRKE RLRTEADAKK LEILSKEIDR
LPNIMAEIAK EDEEKEKVRI RRNMAKEERL KSAPRRLGRH KFEPAPVQVM LTEEISGSLR
KLKGCSNLAR DRFKSIEKRG ILAPSKKISK RRRR
//
