ID   I1HW17_BRADI            Unreviewed;       852 AA.
AC   I1HW17;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   24-JAN-2024, entry version 57.
DE   RecName: Full=Extra-large guanine nucleotide-binding protein 3 {ECO:0008006|Google:ProtNLM};
GN   Name=100825632 {ECO:0000313|EnsemblPlants:KQJ92764};
GN   ORFNames=BRADI_3g00530v3 {ECO:0000313|EMBL:KQJ92764.1};
OS   Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX   NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQJ92764};
RN   [1] {ECO:0000313|EMBL:KQJ92764.1, ECO:0000313|EnsemblPlants:KQJ92764}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQJ92764.1,
RC   ECO:0000313|EnsemblPlants:KQJ92764};
RX   PubMed=20148030; DOI=10.1038/nature08747;
RG   International Brachypodium Initiative;
RT   "Genome sequencing and analysis of the model grass Brachypodium
RT   distachyon.";
RL   Nature 463:763-768(2010).
RN   [2] {ECO:0000313|EMBL:KQJ92764.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQJ92764.1};
RG   The International Brachypodium Initiative;
RA   Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA   Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA   Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT   "WGS assembly of Brachypodium distachyon.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblPlants:KQJ92764}
RP   IDENTIFICATION.
RC   STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ92764};
RG   EnsemblPlants;
RL   Submitted (AUG-2018) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000882; KQJ92764.1; -; Genomic_DNA.
DR   RefSeq; XP_003574346.1; XM_003574298.3.
DR   AlphaFoldDB; I1HW17; -.
DR   STRING; 15368.I1HW17; -.
DR   EnsemblPlants; KQJ92764; KQJ92764; BRADI_3g00530v3.
DR   GeneID; 100825632; -.
DR   Gramene; KQJ92764; KQJ92764; BRADI_3g00530v3.
DR   KEGG; bdi:100825632; -.
DR   eggNOG; KOG0082; Eukaryota.
DR   HOGENOM; CLU_006703_0_0_1; -.
DR   InParanoid; I1HW17; -.
DR   OMA; DYDQVGP; -.
DR   OrthoDB; 1221906at2759; -.
DR   Proteomes; UP000008810; Chromosome 3.
DR   GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR   GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   CDD; cd00066; G-alpha; 1.
DR   Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR001019; Gprotein_alpha_su.
DR   InterPro; IPR011025; GproteinA_insert.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10218:SF334; EXTRA-LARGE GUANINE NUCLEOTIDE-BINDING PROTEIN 3; 1.
DR   PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR   Pfam; PF00503; G-alpha; 1.
DR   PRINTS; PR00318; GPROTEINA.
DR   SMART; SM00275; G_alpha; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR   PROSITE; PS51882; G_ALPHA; 1.
PE   4: Predicted;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          112..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   852 AA;  96610 MW;  F548EF8B55AA8F62 CRC64;
     MAEAMDSGSW QDMMRRILPP GTPIPEAPPN LDYSIALEYD GPPVPYELPR VDPVEIPSTV
     PTAEPVSGPQ GFLGNGGGLP VAPVVARIAR PVPTQAGAAG GGSSESVNSV LQNEEFDDED
     DSRSQSHGSA QSSPGPRNGG HDGRRAQMVT FGFTPDSKYE SNEFDEMSEQ FVAVSKKDRK
     RRKPCNRCGK RKWESKEACL VCDARYCGHC VLRMMGSMPE GRKCVTCIGL PIDEFKRSKL
     GKNSRTLSRL LSPLEVRQIL KAEKECQANQ LRPEQLIVNG CPLRQEELTD LLSCSRPPHK
     LKPGKYWYDK ESGLWGKEGQ KPGRIVSSNL NFSGKLHAKA SNGNTQVFIN GREITKSELK
     ILKVANVQCP RDTHFWVYDD GRYEEEGQNN IKGKIWESAL TRFACALFSL PVPPGDSNGT
     KDEITYLPRT VPDYLDQKRI QKLLLLGPPS AGTSTIFKQA KYLYATRFTQ EELDGIKLMI
     QSNMFKYLGI LLEGRERFEE ETLSRLHCTI SEDEAAQQDE NKANDSNSCI YSINARLKKF
     SDWLLDIIAM GDLDAFFPAA TREYAPFVDE MWKDPAIQAT YKRKDELHFL PDVAEYFLSR
     AIEVSSNEYE PSEKDVIFAE GVTQGNGLSF IEFTLDDRSP MSEPFIDNPE AHSQPLTKYQ
     LIRVNAKGMN DGCKWVEMFE DVRMVIFCVA LSDYDQVGPP VNGNSRLLLN KMIQSKELFE
     ATIRQPCFCD TPFVLVLNKY DLFEEKINRA PLSTCEWFND FSPVRTHNNN QSLAQQAYYY
     IAMKFKDMYA AHTNRKLFVW QARGRDRQTV DEAFKYIREV LKWEEEKDEN YYQEESFYST
     TEMSSSPFIR AE
//