ID I1HY09_BRADI Unreviewed; 486 AA.
AC I1HY09;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=BRCA1-associated protein {ECO:0008006|Google:ProtNLM};
GN Name=100836464 {ECO:0000313|EnsemblPlants:KQJ93694};
GN ORFNames=BRADI_3g06180v3 {ECO:0000313|EMBL:KQJ93694.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ93694.1};
RN [1] {ECO:0000313|EMBL:KQJ93694.1, ECO:0000313|EnsemblPlants:KQJ93694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ93694.1,
RC ECO:0000313|EnsemblPlants:KQJ93694};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ93694.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ93694.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ93694}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ93694};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; CM000882; KQJ93694.1; -; Genomic_DNA.
DR RefSeq; XP_014755727.1; XM_014900241.1.
DR AlphaFoldDB; I1HY09; -.
DR STRING; 15368.I1HY09; -.
DR EnsemblPlants; KQJ93694; KQJ93694; BRADI_3g06180v3.
DR GeneID; 100836464; -.
DR Gramene; KQJ93694; KQJ93694; BRADI_3g06180v3.
DR KEGG; bdi:100836464; -.
DR eggNOG; KOG0804; Eukaryota.
DR HOGENOM; CLU_009969_1_0_1; -.
DR InParanoid; I1HY09; -.
DR OMA; SPNQYMA; -.
DR OrthoDB; 123540at2759; -.
DR Proteomes; UP000008810; Chromosome 3.
DR ExpressionAtlas; I1HY09; baseline.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0007265; P:Ras protein signal transduction; IBA:GO_Central.
DR CDD; cd16457; RING-H2_BRAP2; 1.
DR CDD; cd12437; RRM_BRAP2_like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR011422; BRAP2/ETP1_RRM.
DR InterPro; IPR047243; RING-H2_BRAP2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR24007; BRCA1-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR24007:SF7; BRCA1-ASSOCIATED PROTEIN; 1.
DR Pfam; PF07576; BRAP2; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 168..208
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 202..295
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 336..443
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 53669 MW; D63C27DE03580796 CRC64;
MATANDSGDP ASPSSSTRAL ESVPFSSGNP RIEETRGVVL LHPDPPAAAA APSLSSDLPV
GRKPWVCVPA VPNHMTYADF CRFCGAFVPH MLEMRIVRID GADDQYSVLI KFDTLSSTDS
FYKHFNGKRF SSMEGDVSRV RFVEDVHYTQ LIEHAHSSVT SSAEQPTCPV CLERLDQDPG
GILTTICNHS FHCSCISKWT DSSCPVCRYC QQQPEKSMCS ICGTSENLWI CVICGNVGCG
RYKGGHAIEH WKETEHCYSL ELETQKVWDY AGDNYVHRLI QSKTDGKLVE YNCYGDHGAD
GMCSICSGDA GMDEALLNSK VEAIVEEYND LLTSQLDKQR NYYEALLLEV KEENEKEISA
ATAKAVSIKL QKLQAKLDKC IEEKSFLDDI NTNLVKNQEM WIERIRKVQE REQAALRLKD
EKIEKLEAEL TDLIAHIECH NAVAAAPESI ASEIQGGSVL PGPSAASSSS ISGGSPIRAT
RSRKRN
//
