ID I1I4M1_BRADI Unreviewed; 473 AA.
AC I1I4M1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=3-ketoacyl-CoA synthase {ECO:0000256|PIRNR:PIRNR036417};
DE EC=2.3.1.- {ECO:0000256|PIRNR:PIRNR036417};
GN Name=100836571 {ECO:0000313|EnsemblPlants:KQJ97060};
GN ORFNames=BRADI_3g28560v3 {ECO:0000313|EMBL:KQJ97060.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ97060.1};
RN [1] {ECO:0000313|EMBL:KQJ97060.1, ECO:0000313|EnsemblPlants:KQJ97060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ97060.1,
RC ECO:0000313|EnsemblPlants:KQJ97060};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ97060.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ97060.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ97060}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ97060};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|PIRNR:PIRNR036417}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|PIRNR:PIRNR036417}.
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DR EMBL; CM000882; KQJ97060.1; -; Genomic_DNA.
DR RefSeq; XP_003574048.1; XM_003574000.3.
DR AlphaFoldDB; I1I4M1; -.
DR STRING; 15368.I1I4M1; -.
DR EnsemblPlants; KQJ97060; KQJ97060; BRADI_3g28560v3.
DR GeneID; 100836571; -.
DR Gramene; KQJ97060; KQJ97060; BRADI_3g28560v3.
DR KEGG; bdi:100836571; -.
DR eggNOG; ENOG502QPV6; Eukaryota.
DR HOGENOM; CLU_013238_3_1_1; -.
DR InParanoid; I1I4M1; -.
DR OMA; CCIQQED; -.
DR OrthoDB; 930987at2759; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000008810; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR012392; 3-ktacl-CoA_syn.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013601; FAE1_typ3_polyketide_synth.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR31561; 3-KETOACYL-COA SYNTHASE; 1.
DR PANTHER; PTHR31561:SF197; 3-KETOACYL-COA SYNTHASE; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR Pfam; PF08392; FAE1_CUT1_RppA; 1.
DR PIRSF; PIRSF036417; 3-ktacl-CoA_syn; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|PIRNR:PIRNR036417};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|PIRNR:PIRNR036417}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..473
FT /note="3-ketoacyl-CoA synthase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014095060"
FT DOMAIN 26..319
FT /note="FAE"
FT /evidence="ECO:0000259|Pfam:PF08392"
FT DOMAIN 350..432
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
FT ACT_SITE 176
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 255
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 353
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 357
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 386
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
FT ACT_SITE 390
FT /evidence="ECO:0000256|PIRSR:PIRSR036417-1"
SQ SEQUENCE 473 AA; 52478 MW; 740BEF2ED3485160 CRC64;
MELATMVTLT LLALSLATLA RVLVARARMR RCYLLDYVCY KGTDDRKLPT DLCGEIIQRN
KLLGLEEYKF LLKVIVNSGI GEETYGPRNI IAGGDASPDR VNEGMEEMDE TFHAVLDELF
ARSAAPGGIG VRPEDVDLLV VNVSMFSPAP SLSARVVRRY GLREDVKVFN LTGMGCSATL
IALDLANNFF RTHASKVALV MTSESIAPNW YPGNKRSFML GNCLFRSGGC AYFLTNSPRL
RPHAKLRLRH VVRTHTGASD ESYNCALQME DDAGRPGFHL GKELPRAAVG AFVKNLRVLA
PRVLPLPELL RLAYSTLSSR LARRSNNNNN NNNNTKPKSS SAMTIRMKAG VDHFCVHTGG
AAVIDGVGKG LTLTEHDIEP SRMTLHRFGN TSASSVWYVL SYMEAKRRLK RGDRVLMLTF
GAGFKCNSCV WTVEKDDIAD AGVWKDCIHE YPPKEIRNPF MEKYGFVKDM MAL
//
