ID I1I964_BRADI Unreviewed; 1205 AA.
AC I1I964;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100825836 {ECO:0000313|EnsemblPlants:KQJ99244};
GN ORFNames=BRADI_3g41960v3 {ECO:0000313|EMBL:KQJ99244.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ99244.1};
RN [1] {ECO:0000313|EMBL:KQJ99244.1, ECO:0000313|EnsemblPlants:KQJ99244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ99244.1,
RC ECO:0000313|EnsemblPlants:KQJ99244};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ99244.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ99244.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ99244}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ99244};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM000882; KQJ99244.1; -; Genomic_DNA.
DR AlphaFoldDB; I1I964; -.
DR EnsemblPlants; KQJ99244; KQJ99244; BRADI_3g41960v3.
DR Gramene; KQJ99244; KQJ99244; BRADI_3g41960v3.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_8_8_1; -.
DR InParanoid; I1I964; -.
DR OMA; MMMVPLE; -.
DR OrthoDB; 344735at2759; -.
DR Proteomes; UP000008810; Chromosome 3.
DR ExpressionAtlas; I1I964; differential.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IBA:GO_Central.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1219; OS08G0543500 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 9..98
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 185..391
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1205 AA; 136336 MW; C838E9FE62165E0F CRC64;
MADLLLLPVV RTAAGKAADA VVRRMTGMWG IDDDRLKLER QLLAVQCKLA DAEIKSETNQ
YIRRWMKDFR TVAYEANDVL DGFQYEALRR EARIGESKTR KVLNQFTSRS PLLFRLTMSR
DLNNVLEKIN NLVEEMNKFG LVEHAEPPQL ICRQTHSGLD DSADIFGRDD DKGVVLKLLL
GQHNQRKVQV LPIFGMGGLG KTTLAKMVYN NHRVQQHFQL TMWHCVSENF EAVAVVKSII
ELATKGRCEL PDTVELLRVR LQEVIGQKRY MLVLDDVWNE EVRKWEDELK PLLCSVGGPG
SVILVTCRSR QVASIMGTVG LHELPCLRED DSWELFSKKA FSRGVEEQAE LVTIGKRIAK
KCRGLPLALK IMGGLMSSKQ QVQEWEAIAE SNIGDNIGGK YEILPILKLS YRHLSAEMKQ
CFAFCAVFAK DYEMEKDILI QLWMANGFIQ EEGTMDLAQK GEYIFYDLVW RSFLQDVKVN
LRRFIATSYE SIGCKMHDLM HDLAKDVAHG CVTIEELIQQ KASIQHVRHM WIDAQYELKP
NSRVFKGMTS LHTLLAPSKS HKDLMEVKGM PLRALHCYSS SIIHSPVRHA KHLRYLDLSW
SDIFTLPDSI SVLYNLQTLR LDGCSKLQHL PEGISTMRKL IHLYLFGCDS LERMPPNISL
LNNLHTLTTF VVDTEAGYGI EELKDLCQLG NRLELYNLRK IRSGQNAKKA SLHQKHNLSE
LLLCWGRRKS YEPGEEFCNE EVLVSLTPHS KLKVLEVYGY GGLEISHLMG DPQMFRCLRK
FYISNCPRCK TLPIVWISMS LEYLSVANMG NLTTLWKSIK AEAEGYSTLL QFFPKLKEIV
LDELPILERW AENCAGEPNS LVMFPLLEKL TIIKCPKLAS VPGSPVLKDL FIKECCSLPI
SSLAHLRTLI YLAYDGTGPV STSMSLGSWP SLVNLEVTSL ATMMMVPLED RQNQSQIPLE
ALRSLTLNGP NCFAKTPVLS KLHHVLWECF AFVEELKIFG CGELVRWPVE ELQSLAHLRY
LAISLCDNLK GKGSSSEETL PLPQLERLHI EGCISLLEIP KLLPSLEQLA ISSCMNLEAL
PSNLGDLAKL RELSLHSCEG LKVLPDGMDG LTSLEKLAIG YCPRIEKLPE GLLQQLPALK
CLCILGCPNL GQRCREGGEY SHLVSSIPDK VIRLEEYRVT STQKEPNTKK FLRRLLPSCG
ADYNN
//
