ID I1IBQ6_BRADI Unreviewed; 756 AA.
AC I1IBQ6;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100843679 {ECO:0000313|EnsemblPlants:KQK00403};
GN ORFNames=BRADI_3g49170v3 {ECO:0000313|EMBL:KQK00403.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK00403.1};
RN [1] {ECO:0000313|EMBL:KQK00403.1, ECO:0000313|EnsemblPlants:KQK00403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK00403.1,
RC ECO:0000313|EnsemblPlants:KQK00403};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK00403.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK00403.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK00403}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK00403};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; CM000882; KQK00403.1; -; Genomic_DNA.
DR RefSeq; XP_010235726.1; XM_010237424.2.
DR AlphaFoldDB; I1IBQ6; -.
DR STRING; 15368.I1IBQ6; -.
DR EnsemblPlants; KQK00403; KQK00403; BRADI_3g49170v3.
DR GeneID; 100843679; -.
DR Gramene; KQK00403; KQK00403; BRADI_3g49170v3.
DR KEGG; bdi:100843679; -.
DR eggNOG; ENOG502QQPF; Eukaryota.
DR HOGENOM; CLU_000288_43_5_1; -.
DR InParanoid; I1IBQ6; -.
DR OMA; VGKETCR; -.
DR OrthoDB; 390468at2759; -.
DR Proteomes; UP000008810; Chromosome 3.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR045274; WAK-like.
DR PANTHER; PTHR27005:SF279; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR27005; WALL-ASSOCIATED RECEPTOR KINASE-LIKE 21; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..756
FT /note="Protein kinase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014095175"
FT DOMAIN 307..351
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 431..714
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 460
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 756 AA; 81969 MW; 4964C64306F98A06 CRC64;
MQAEIFLTLL AVLASACPAA GAAWQPSEAC QRRCGDVDIP YPFGIGRDCY LYTGDNDITF
GLTCNLTADG IYKPFCYEQE ILSVSVARGK ARVRTDIQPW CYNGTSRSMD PQFAPWIDFS
DSSFMLSDEE NRFTVVGCNS LAYVSSMEGS QFTNGYEYMT GCMATCPGGG RVENGSCSGM
GCCQAAIPRG VNTYQEKFNT SRAAAGSSSG PCSYAVLVEA AAFDFRTGYV AADGGGGFME
STGGTVPLVL DWVVGKETCL EAKRNASASA CVSGNSACVD SRNGPGYLCN CSIGYRGNPC
LLDGCRDINE CEDRSIEYPC SVPGTCVNTP GGFSCACPDK TTGNAYTGTC EAKKSLLGVH
VAMGVSVSVV VLVISMACAC IIREKRSLDT VKRKYFKQHG GLLLFEEMKS KQGISFTLFT
REELEEATSK FDERNVLGKG GNGTVYKGTL KDGRTVAIKK CKLTNERQKK EFGKEMLILS
QINHRNIVKL YGCCLEVEVP MLVYEFIPNG TLYQLVHGSG GSLLVPLATR VKIAHEAAEA
LAYLHSWASP PIIHGDVKSP NILIDESYAV KVADFGASTL APTDEAQLVT FVQGTCGYLD
PEYMQTCKLT DRSDVYSFGV VLLELLTRRK ALNLQATEDE DKTLSSQFLL AASANRLDEI
VDAQIVSQQS IELIEQMAEL AKQCLRMDSE KRPSMREVAE ELGKLRKVLQ HPWGQQSSGE
LQGLLARSPN TYSEIELSNA CVSYDDSAYI GVQSPR
//
