ID I1IBR0_BRADI Unreviewed; 637 AA.
AC I1IBR0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Photolyase/cryptochrome alpha/beta domain-containing protein {ECO:0000259|PROSITE:PS51645};
GN Name=100838321 {ECO:0000313|EnsemblPlants:KQK00407};
GN ORFNames=BRADI_3g49204v3 {ECO:0000313|EMBL:KQK00407.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK00407.1};
RN [1] {ECO:0000313|EMBL:KQK00407.1, ECO:0000313|EnsemblPlants:KQK00407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK00407.1,
RC ECO:0000313|EnsemblPlants:KQK00407};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK00407.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK00407.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK00407}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK00407};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC {ECO:0000256|ARBA:ARBA00005862}.
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DR EMBL; CM000882; KQK00407.1; -; Genomic_DNA.
DR RefSeq; XP_003575393.1; XM_003575345.3.
DR AlphaFoldDB; I1IBR0; -.
DR STRING; 15368.I1IBR0; -.
DR EnsemblPlants; KQK00407; KQK00407; BRADI_3g49204v3.
DR GeneID; 100838321; -.
DR Gramene; KQK00407; KQK00407; BRADI_3g49204v3.
DR KEGG; bdi:100838321; -.
DR eggNOG; KOG0133; Eukaryota.
DR HOGENOM; CLU_010348_5_0_1; -.
DR InParanoid; I1IBR0; -.
DR OMA; ETLIDWD; -.
DR OrthoDB; 124765at2759; -.
DR Proteomes; UP000008810; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016604; C:nuclear body; IEA:EnsemblPlants.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:EnsemblPlants.
DR GO; GO:0009882; F:blue light photoreceptor activity; IEA:InterPro.
DR GO; GO:0003904; F:deoxyribodipyrimidine photo-lyase activity; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0071949; F:FAD binding; IBA:GO_Central.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:EnsemblPlants.
DR GO; GO:0006338; P:chromatin remodeling; IEA:EnsemblPlants.
DR GO; GO:0010617; P:circadian regulation of calcium ion oscillation; IEA:EnsemblPlants.
DR GO; GO:0032922; P:circadian regulation of gene expression; IBA:GO_Central.
DR GO; GO:0051607; P:defense response to virus; IEA:EnsemblPlants.
DR GO; GO:0043153; P:entrainment of circadian clock by photoperiod; IBA:GO_Central.
DR GO; GO:0072387; P:flavin adenine dinucleotide metabolic process; IEA:EnsemblPlants.
DR GO; GO:0048574; P:long-day photoperiodism, flowering; IEA:EnsemblPlants.
DR GO; GO:0009638; P:phototropism; IEA:EnsemblPlants.
DR GO; GO:0009911; P:positive regulation of flower development; IEA:EnsemblPlants.
DR GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:EnsemblPlants.
DR GO; GO:1901371; P:regulation of leaf morphogenesis; IEA:EnsemblPlants.
DR GO; GO:0010075; P:regulation of meristem growth; IEA:EnsemblPlants.
DR GO; GO:2000028; P:regulation of photoperiodism, flowering; IEA:EnsemblPlants.
DR GO; GO:0009646; P:response to absence of light; IEA:EnsemblPlants.
DR GO; GO:0010244; P:response to low fluence blue light stimulus by blue low-fluence system; IEA:EnsemblPlants.
DR GO; GO:1902347; P:response to strigolactone; IEA:EnsemblPlants.
DR GO; GO:0009414; P:response to water deprivation; IEA:EnsemblPlants.
DR GO; GO:0010118; P:stomatal movement; IEA:EnsemblPlants.
DR Gene3D; 1.25.40.80; -; 1.
DR Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR InterPro; IPR014134; Cryptochrome_pln.
DR InterPro; IPR018394; DNA_photolyase_1_CS_C.
DR InterPro; IPR006050; DNA_photolyase_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR02766; crypt_chrom_pln; 1.
DR PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR PANTHER; PTHR11455:SF18; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, MITOCHONDRIAL; 1.
DR Pfam; PF00875; DNA_photolyase; 1.
DR Pfam; PF03441; FAD_binding_7; 1.
DR PRINTS; PR00147; DNAPHOTLYASE.
DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR PROSITE; PS00394; DNA_PHOTOLYASES_1_1; 1.
DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|ARBA:ARBA00022991};
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW 1}; Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 5..135
FT /note="Photolyase/cryptochrome alpha/beta"
FT /evidence="ECO:0000259|PROSITE:PS51645"
FT REGION 529..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 233
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 245..249
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 288
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 388..390
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT SITE 322
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
FT SITE 375
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
FT SITE 398
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
SQ SEQUENCE 637 AA; 71913 MW; 1EC981D858C7B8FC CRC64;
MGGSERTIVW FRRDLRIDDN PALAAAARDG SVLPIFIWCP ADEGQFYPGR CSRWWLKESL
AHLGKSLEAL GCPLHLIRAE ESSLAALLQC VHSIGATRVV YNHLYDPVSL VRDDNVKNEL
SVLGISFESF NGDLLYQPWE VYDDNGHAFT TFNLYWEQCL KLPIEVSPSL APWRLVPVPG
IENLQSCSID DLGLESSKDE ESSNALLSRA WSPGWRNAEK TLEEFVCQGL QDYSKHGMKV
AGATTSLLSP YLHYGELSVR KIYQLVRMQQ IKWENEGKSE AGESINLFLQ SVGLREYSRY
LCFNFPFTHE RSLLGNLKHY PWQVDEDRFK SWRQGMTGYP LVDAGMRELW ATGWTHNRIR
VIVSSFAVKF LLIPWTWGMK YFWDVLLDAD LESDILGWQY ISGSLPDGHE LSRLDNPEVQ
GQKYDPDGEY VRTWIPELAR MPTEWIHHPW DAPSSILQVA GVELGFNYPK PIVELHTARE
CLDDAISTMW QLDTAEKLAE LDGEVVEDNL SHIKSFDIPK VVLKELSPSA PPIDQRVPSS
SGRNHELQPK ASKTEDTGSI VNSLISRKRY SSGSAFDVPS CSCSVEVRSQ NQDTGCSLVE
SSRYVSHKTE RNCADKAEDD DSADSGTSIS RPSKKPA
//
