ID I1ILC0_BRADI Unreviewed; 648 AA.
AC I1ILC0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Aminopeptidase P1 {ECO:0008006|Google:ProtNLM};
GN Name=100825865 {ECO:0000313|EnsemblPlants:KQJ88315};
GN ORFNames=BRADI_4g16980v3 {ECO:0000313|EMBL:KQJ88315.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQJ88315};
RN [1] {ECO:0000313|EMBL:KQJ88315.1, ECO:0000313|EnsemblPlants:KQJ88315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ88315.1,
RC ECO:0000313|EnsemblPlants:KQJ88315};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ88315.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ88315.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ88315}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ88315};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766, ECO:0000256|RuleBase:RU000590}.
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DR EMBL; CM000883; KQJ88315.1; -; Genomic_DNA.
DR RefSeq; XP_003577500.1; XM_003577452.3.
DR AlphaFoldDB; I1ILC0; -.
DR STRING; 15368.I1ILC0; -.
DR MEROPS; M24.037; -.
DR EnsemblPlants; KQJ88315; KQJ88315; BRADI_4g16980v3.
DR GeneID; 100825865; -.
DR Gramene; KQJ88315; KQJ88315; BRADI_4g16980v3.
DR KEGG; bdi:100825865; -.
DR eggNOG; KOG2413; Eukaryota.
DR HOGENOM; CLU_011781_2_2_1; -.
DR InParanoid; I1ILC0; -.
DR OMA; VHEYPPS; -.
DR OrthoDB; 869at2759; -.
DR Proteomes; UP000008810; Chromosome 4.
DR ExpressionAtlas; I1ILC0; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 12..136
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 336..572
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 585..644
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 648 AA; 72288 MW; 1ED0E7502E3BABC7 CRC64;
MATSAAARDQ HLDELRALMA AHSPPIHALI VPSEDAHQSE YVSERDKRRQ FISGFTGSAG
LALITTKEAL LWTDGRYFLQ ASQQLSDSWK LMRMGEDPPV EVWIADNLSD EAVIGIDPWC
ISVDAAQRYE QSFLKKHQTL FQLSSDLVDE IWKDRPPNDA LPVVVHPVEF AGRSVAEKIK
ELREKLEHEK ANGIIITALD EVAWLYNVRG ADVHFSPVVH SFAIVTLHNA FFYVDKRKVT
AEVQNYMAEN GIDIREYHTV QPDVSLLASG HLKGSAVNGS LQVENDINKV EHSKIWIDSN
SCCLALYSKL STNQVLMLQS PIALPKAVKN PMELDGLRKA HIRDGAAVVQ YLAWLDNQMQ
ENYGAPGYFS EANGSQRKEH LEIKLTEVSV SDKLEGFRAT KELFKGLSFP TISSVGPNAA
IIHYSPEANT CAELDADKIY LCDSGAQYLD GTTDITRTVH FGRPSEHEKS CYTAVLKGHI
ALDAAVFPNG TTGHALDILA RTPLWKSGLD YRHGTGHGIG SYLNVHEGPH LISFRPSARN
VPLQASMTVT DEPGYYEDGN FGIRLENVLI VKGADTKFNF GEKGYLSFEH ITWAPYQTKL
INTTLLTPEE IDWVNMYHSD CRKILGSYLN EQEKEWLRKA TEPITVSS
//
