ID I1KZU7_SOYBN Unreviewed; 507 AA.
AC I1KZU7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Aspartic proteinase {ECO:0008006|Google:ProtNLM};
GN Name=547943 {ECO:0000313|EnsemblPlants:KRH36484};
GN ORFNames=GLYMA_09G005600 {ECO:0000313|EMBL:KRH36484.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EnsemblPlants:KRH36484};
RN [1] {ECO:0000313|EMBL:KRH36484.1, ECO:0000313|EnsemblPlants:KRH36484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH36484};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH36484.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH36484}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH36484};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH36484.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH36484.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR EMBL; CM000842; KRH36484.1; -; Genomic_DNA.
DR RefSeq; XP_003534602.1; XM_003534554.3.
DR AlphaFoldDB; I1KZU7; -.
DR SMR; I1KZU7; -.
DR STRING; 3847.I1KZU7; -.
DR MEROPS; A01.A02; -.
DR PaxDb; 3847-GLYMA09G00810-1; -.
DR EnsemblPlants; KRH36484; KRH36484; GLYMA_09G005600.
DR GeneID; 547943; -.
DR Gramene; KRH36484; KRH36484; GLYMA_09G005600.
DR KEGG; gmx:547943; -.
DR eggNOG; KOG1339; Eukaryota.
DR HOGENOM; CLU_013253_3_1_1; -.
DR InParanoid; I1KZU7; -.
DR OMA; EGDAAQC; -.
DR OrthoDB; 1120702at2759; -.
DR Proteomes; UP000008827; Chromosome 9.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd06098; phytepsin; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR Gene3D; 1.10.225.10; Saposin-like; 1.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR033869; Phytepsin.
DR InterPro; IPR007856; SapB_1.
DR InterPro; IPR008138; SapB_2.
DR InterPro; IPR011001; Saposin-like.
DR InterPro; IPR008139; SaposinB_dom.
DR PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR47966:SF15; FUNGAL PROTEINASE A, ASPARTIC PROTEINASE SUPERFAMILY PROTEIN; 1.
DR Pfam; PF00026; Asp; 1.
DR Pfam; PF05184; SapB_1; 1.
DR Pfam; PF03489; SapB_2; 1.
DR PRINTS; PR00792; PEPSIN.
DR SMART; SM00741; SapB; 2.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF47862; Saposin; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 2.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
DR PROSITE; PS50015; SAP_B; 2.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750,
KW ECO:0000256|RuleBase:RU000454};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR601461-2};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000454};
KW Protease {ECO:0000256|RuleBase:RU000454};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..507
FT /note="Aspartic proteinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014578047"
FT DOMAIN 83..504
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT DOMAIN 313..353
FT /note="Saposin B-type"
FT /evidence="ECO:0000259|PROSITE:PS50015"
FT DOMAIN 377..418
FT /note="Saposin B-type"
FT /evidence="ECO:0000259|PROSITE:PS50015"
FT ACT_SITE 101
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 288
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT DISULFID 114..120
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
SQ SEQUENCE 507 AA; 55276 MW; 541EA3BC518AC63A CRC64;
MGNMSNVVVF CFCLWTLLFS LVFCAPNDGL GRIGLKKVKL NTHDVEGLKE FRSSIRKHHL
QNILGGAEET DVVALKNYLD AQYYGEIAIG TPPQKFTVIF DTGSSNLWVP SSKCYFSIAC
FMHARYRSSQ SSTYRENGTS AAIQYGTGAI SGFFSNDDVK VGDIVVKDQE FIEATREPGV
TFVAAKFDGI LGLGFQDISV GYAVPVWYSM VEQGLVKDPV FSFWLNRKPE EENGGELVFG
GADPAHYKGK HTYVPVTRKG YWQFDMGDVL IAGKPTGYCA DDCSAIADSG TSLLAGPTTV
VTMINQAIGA SGVVSKECRS VVNQYGQTIL ELLLAEAKPK KICSQIGLCT FDGTHGVSMG
IESVVDKNER KSSGSIRDAG CSACEMAVIW MQNQLRQNQT EDRIIDYANE LCDKLPNPMG
QSSVDCEKLS SMPIVSFTIG GKVFDLSPQE YILKVGEGPE AQCISGFTAL DVPPPRGPLW
ILGDVFMGRY HTIFDYGKLR VGFAEAA
//
