ID I1MN42_SOYBN Unreviewed; 1012 AA.
AC I1MN42;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 2.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
GN Name=100806748 {ECO:0000313|EnsemblPlants:KRH08051};
GN ORFNames=GLYMA_16G126400 {ECO:0000313|EMBL:KRH08051.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EnsemblPlants:KRH08051};
RN [1] {ECO:0000313|EMBL:KRH08051.1, ECO:0000313|EnsemblPlants:KRH08051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH08051};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH08051.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH08051}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH08051};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH08051.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH08051.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361199};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
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DR EMBL; CM000849; KRH08051.1; -; Genomic_DNA.
DR RefSeq; XP_003548841.1; XM_003548793.3.
DR AlphaFoldDB; I1MN42; -.
DR SMR; I1MN42; -.
DR STRING; 3847.I1MN42; -.
DR PaxDb; 3847-GLYMA16G23600-1; -.
DR EnsemblPlants; KRH08051; KRH08051; GLYMA_16G126400.
DR GeneID; 100806748; -.
DR Gramene; KRH08051; KRH08051; GLYMA_16G126400.
DR KEGG; gmx:100806748; -.
DR eggNOG; KOG1959; Eukaryota.
DR HOGENOM; CLU_004690_2_0_1; -.
DR InParanoid; I1MN42; -.
DR OMA; KVEPHAE; -.
DR OrthoDB; 5474711at2759; -.
DR Proteomes; UP000008827; Chromosome 16.
DR GO; GO:0004559; F:alpha-mannosidase activity; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10810; GH38N_AMII_LAM_like; 1.
DR Gene3D; 2.60.40.1360; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR048534; Man2a1-like_dom.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF61; ALPHA-MANNOSIDASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR Pfam; PF21260; Laman-like_dom; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW Hydrolase {ECO:0000256|RuleBase:RU361199};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361199};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Signal {ECO:0000256|RuleBase:RU361199};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT CHAIN 26..1012
FT /note="Alpha-mannosidase"
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT /id="PRO_5014579014"
FT DOMAIN 361..435
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1012 AA; 114102 MW; CB40E20CC2D657B3 CRC64;
MGNLAAESLC ALLLLCFYGK LIVSAKYMKY NTGASIVPGK LNVHLVPHSH DDVGWLKTID
QYYVGSNNSI QGACVENVLD SVVVSLQKDP NRKFVFAEMA FFHRWWVEQS PETQEQVRKL
VDAGQLEFIN GGWCMHDEAA THYIDMIDQT TLGHRFIKDQ FNKTPTVGWQ IDPFGHSAVQ
AYLLGAELGF DSIHFARIDY QDRAKRKADK SLEVVWRGSK TFGSSAQIFA NTFPVHYSAP
NGFNFEVNNP DVDVGPVQDD PLIFDYNVKQ RVKEFIDAAT TQANVTRTNH IMWTMGDDFQ
YQYAESWFKQ MDKLIHYVNK DGRVNALYST PSIYTNAKNA ANQLWPLKTD DYFPYADSPN
AYWTGYFTSR PALKRYVRML SGYYLAARQL EFLVGKQSTK YNTYDLGDAL GIAQHHDAVS
GTAKQHTTND YAKRLAIGAY EAEAVVSSSL ACLTRKQSGD KCSTPASAFA QCQLLNISYC
PPAEDNIPEA KSLVVVVYNP LGWNRTDIVK IPVNDANLVV KDSSGNKLEV QYVDVDDVTT
NLRKFYVKAY VGVSPKQSPK YWLLFQVSVP PLGWSTYFIS KATRKGTRRK DLSHTNSQKG
DTINIGSGNL KMSFSSTSGQ LKRMYNSRTG VDIPIQQSYL WYGSSEGDSD PQASGAYIFR
PNGSPPNIVS RSVPTKVIRG PLVDEVHQKF SSWIYQVTRL YKDKEHAEIE FTIGPIPTDD
GVGKEVITRM TANMATNKEF YADSNGRDFL KRVRDHREDW PLQVTQPVAG NYYPLNLGIY
TKDEKSEFSV LVDRATGGAS IKDGEVELML HRRILHDDSR GVGEPLDEQV CVNNNNTCEG
LTVRGNYYIS IHKLGVGSRW RRTTGQEIYS PFLVAFTHEI SENWKSSHLT KGTIMDPNYS
LPPNIALITL EELDGGIVLL RLAHLYERSE DAEYSTLTKV ELKKLFAMKT IRELKEVSLS
SNQEKSEMKR MTWKVEGDKG QEPQAVRGGP VSYHNLVVEL GPMEIRTFLL KF
//
