ID I1P2W6_ORYGL Unreviewed; 1609 AA.
AC I1P2W6;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=UDP-glucose:glycoprotein glucosyltransferase {ECO:0008006|Google:ProtNLM};
OS Oryza glaberrima (African rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA02G0232200.1, ECO:0000313|Proteomes:UP000007306};
RN [1] {ECO:0000313|Proteomes:UP000007306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA Zuccolo A.;
RT "The complete genome of Oryza glaberrima.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORGLA02G0232200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC {ECO:0000256|ARBA:ARBA00004319}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 8 family.
CC {ECO:0000256|ARBA:ARBA00006351}.
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DR STRING; 4538.I1P2W6; -.
DR EnsemblPlants; ORGLA02G0232200.1; ORGLA02G0232200.1; ORGLA02G0232200.
DR Gramene; ORGLA02G0232200.1; ORGLA02G0232200.1; ORGLA02G0232200.
DR eggNOG; KOG1879; Eukaryota.
DR HOGENOM; CLU_002668_1_0_1; -.
DR OMA; KNFYRYV; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000007306; Unassembled WGS sequence.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR CDD; cd06432; GT8_HUGT1_C_like; 1.
DR InterPro; IPR040497; Glyco_transf_24.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR009448; UDP-g_GGtrans.
DR InterPro; IPR040693; UGGT_TRXL_1.
DR InterPro; IPR040694; UGGT_TRXL_2.
DR InterPro; IPR040692; UGGT_TRXL_3.
DR InterPro; IPR040525; UGGT_TRXL_4.
DR PANTHER; PTHR11226; UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR11226:SF0; UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF18404; Glyco_transf_24; 1.
DR Pfam; PF18400; Thioredoxin_12; 1.
DR Pfam; PF18401; Thioredoxin_13; 1.
DR Pfam; PF18402; Thioredoxin_14; 1.
DR Pfam; PF18403; Thioredoxin_15; 1.
DR Pfam; PF06427; UDP-g_GGTase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 51..259
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18400"
FT DOMAIN 347..464
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18401"
FT DOMAIN 475..741
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18402"
FT DOMAIN 758..1001
FT /note="UDP-glucose:glycoprotein glucosyltransferase
FT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18403"
FT DOMAIN 1308..1574
FT /note="Glucosyltransferase 24 catalytic"
FT /evidence="ECO:0000259|Pfam:PF18404"
FT REGION 1578..1609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1583..1597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1609 AA; 181702 MW; CF6BBBA937040030 CRC64;
MEAARGARSR VPVAAVVAVV LVAGLAAGGS AAEIRRQKNV QVALRAKWAG TPLLLEASEL
LSKEWKDLFW DFIDHWKELD KASECLTAKC CVQKIVEDAR SFLSEPLASI FEFSLTLRSA
SPRLVLYRQL AEESLSSIPV KDGTLEQTSG PSTGENFHEA VKGTCCWVDT GSALLLNSAD
LRKWLDGLGK LAVDSTQQPE LFEFDHIYPQ SNITAPIAIF YGAFGTKCFK ELHVHLAEAS
KQGKVRYALR HVLPSGCQAT SSFCGSVGAI DAVTLSGYGV ELALKNMEYK AMDDTAIKKG
VALEDPKTED LSQEVRGFIF SKILERKPAL NAEIMSFRDY LLSSTVSDTL EVWELKDLGH
QTAQRILHAS DPLQSMQEIN QNFPSIVSSL SRMKLDDSIK DEIIANQRMV PPGKSLMALN
GALINIEDLD LYLLMDMVHE ELSLADQFVK LKIPGSAVHK ILSAAPPTES NSFRVDFRSS
HVHYLNNLEE DALYKRWRSN INELLMPVFP GQMRYIRKNL FHAVYVLDPA SVCGAETIDM
VLSLYQDSVP IRFGIILYSS RLISVIEEND GNLPVNNGSK TEEDISILII RLFLYIKETY
STQLAYQFLS NIHKSQNSGD DYNEESVEAH HVEGAFVDSL LSSAKSHPQD VLLKLQKENM
HKQEAEESSR FVHKLGLYKL QCCLLMNGLV HESSEDATMN AMNDELPRIQ EQVYYGHIQS
HTDVLEKFLS ESSYKRYNPS ITGKSTENKR FVSLVGPYHQ GDSTLHDITY LHSHGTTDDA
KPVTHLVAVD ISSKIGIKLL HEAIRYLMAG SNRARVGLLI YVRNDNPSPI LHMKDIFDRT
ISSFSYKEKV LDFLHELCKF YEGQHVPSSG VGDKISTMRE KVYSIAAETG LPVDNYKAWF
TSYSHDAVLR GMNKLSDFLF GKLGLEFGSN AVITNGRVFV VNEGDSFLTD DLGLLESMEY
ELRTKHIYEI IEEIEWTGVD PDDLTSKFYS DVAMLISSSM SIRERPSERA HFEILHAEHS
AIKLNGMSSG VHIDAVIDPL SPAGQKLAPL LRILWRQIEP SMRIVLNPIS SLADLPLKNY
YRFVLPSMDD FSSTDYSVHG PKAFFANMPL SKTLTMNIDV PEPWLVEPVI AIHDLDNILL
ENLGDVITLQ AVFELEALLL TGHCKEKDRD PPRGLQFILG TKRRPHLVDT LVMANLGYWQ
MKVSPGVWYL QLAPGRSADL YELPSKLIAI DSLRGKLMHI EVQKRGGKEH EDLLNADDDN
HFQEKMDNKG WNNNLLKWAS SFISGDSSSK KKDEKISDLK AARQGETINI FSVASGHLYE
RFLKIMILSV LKQTQRPVKF WFIKNYLSPQ FKDVIPHMAQ EYGFEYELVT YKWPTWLHKQ
KEKQRIIWAY KILFLDVIFP LSLRKVIFVD ADQIVRADMG ELYDMNLKGR PLAYTPFCDN
NKEMDGYRFW KQGFWKDHLR GRPYHISALY VVDLAKFRQT ASGDTLRVFY ETLSKDPNSL
SNLDQDLPNY AQHTVPIFSL PQEWLWCESW CGNATKARAK TIDLCNNPMT KEPKLQGAKR
IVPEWVDLDS EARQFTARIL GDNPESPGTT SPPSDTPKSD DKGAKHDEL
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