ID   I1PEU0_ORYGL            Unreviewed;       804 AA.
AC   I1PEU0;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
OS   Oryza glaberrima (African rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA03G0288600.1, ECO:0000313|Proteomes:UP000007306};
RN   [1] {ECO:0000313|Proteomes:UP000007306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA   Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA   Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA   Zuccolo A.;
RT   "The complete genome of Oryza glaberrima.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORGLA03G0288600.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- FUNCTION: May be involved in the transport of sterols.
CC       {ECO:0000256|ARBA:ARBA00003361}.
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DR   STRING; 4538.I1PEU0; -.
DR   EnsemblPlants; ORGLA03G0288600.1; ORGLA03G0288600.1; ORGLA03G0288600.
DR   Gramene; ORGLA03G0288600.1; ORGLA03G0288600.1; ORGLA03G0288600.
DR   eggNOG; KOG1737; Eukaryota.
DR   HOGENOM; CLU_007105_0_1_1; -.
DR   Proteomes; UP000007306; Chromosome 3.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   CDD; cd13294; PH_ORP_plant; 1.
DR   Gene3D; 2.40.160.120; -; 1.
DR   Gene3D; 3.30.70.3490; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR10972:SF216; OXYSTEROL-BINDING PROTEIN HOMOLOG 3; 1.
DR   PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   Pfam; PF15413; PH_11; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW   Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          86..221
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          31..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          139..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          313..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..54
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        146..162
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        321..336
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..358
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        362..380
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   804 AA;  90772 MW;  D25707FC57A81209 CRC64;
     MHPFCCVPPX XXXXXXXXXX AATPAASSAV AGAPAVMPPP PPPLPPPPPR SNSAPPERRA
     LRWAAGGGSG GGNSPPEGVK LNEIVGGGIS GILYKWVNYG RGWRPRWFAL HDGVLSYYKI
     HGPDRIVLSR ETERGAKVIG EDSLRRLSRP STSSSSSAHS NGHHLPRKPI GEIHLKVSSV
     RESRSDDRRF SIFSGTKRLH LRAETREDRA AWVEALQATK EMFPRMSTSE MVGPGDTAAA
     VAVSTERLRQ RLQQEGVSEA AIADSERIVR TEFEVLHKQL MLLKQKQTLL LDTLRQLETE
     KVDLENTLVD ESQRQSKEYG STSRSKNEKY SEGSASESDD YNEPQDPAED ETDDDENIYF
     DTRDFLSSSS FKSSGSDFQR SEAGSDDEDD YPMDGIDTSM KSVGISYPYV RRRKKLPDPV
     EKEKGVSLWS MIKDNIGKDL TKVCLPVYFN EPLSSLQKCF EDLEYSYLID RAYEWGKRGN
     SLMRILSVAA FAVSGYASTD GRSCKPFNPL LGETYEADYP DKGLRFFSEK VSHHPMVVAC
     HCEGTGWRFW ADSNLKSKFW GRSIQLDPVG VLTLEFDDGE VFQWSKVTTS IYNLILGKLY
     CDHYGTMRIQ GNNEYSCKLK FKEQSIIDRN PHQVQGVVQD RSGRTVATLF GKWDESMHYV
     MGDCFGKGKG SENFSEAHLL WKRSKPPKFP TRYNFTRFAI TLNELTAGLK EKLPPTDSRL
     RPDQRCLENG EYERANAEKL RLEQRQRQAR KMQESGWKPR WFAKDKATDT YRYLGGYWES
     REKGSWEGCP DIFGQVPNDL MITD
//