ID   I1PJB1_ORYGL            Unreviewed;       950 AA.
AC   I1PJB1;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=Vacuolar protein sorting-associated protein 41 homolog {ECO:0000256|PIRNR:PIRNR028921};
OS   Oryza glaberrima (African rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA04G0028000.1, ECO:0000313|Proteomes:UP000007306};
RN   [1] {ECO:0000313|Proteomes:UP000007306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA   Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA   Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA   Zuccolo A.;
RT   "The complete genome of Oryza glaberrima.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORGLA04G0028000.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- FUNCTION: Required for vacuolar assembly and vacuolar traffic.
CC       {ECO:0000256|PIRNR:PIRNR028921}.
CC   -!- SIMILARITY: Belongs to the VPS41 family.
CC       {ECO:0000256|ARBA:ARBA00009582, ECO:0000256|PIRNR:PIRNR028921}.
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DR   AlphaFoldDB; I1PJB1; -.
DR   STRING; 4538.I1PJB1; -.
DR   EnsemblPlants; ORGLA04G0028000.1; ORGLA04G0028000.1; ORGLA04G0028000.
DR   Gramene; ORGLA04G0028000.1; ORGLA04G0028000.1; ORGLA04G0028000.
DR   eggNOG; KOG2066; Eukaryota.
DR   HOGENOM; CLU_001285_2_2_1; -.
DR   OMA; PQLVWQD; -.
DR   Proteomes; UP000007306; Unassembled WGS sequence.
DR   GO; GO:0030897; C:HOPS complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005770; C:late endosome; IEA:UniProtKB-UniRule.
DR   GO; GO:0034058; P:endosomal vesicle fusion; IEA:UniProtKB-UniRule.
DR   GO; GO:0009630; P:gravitropism; IEA:EnsemblPlants.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR   GO; GO:0007034; P:vacuolar transport; IEA:UniProtKB-UniRule.
DR   CDD; cd16687; RING-H2_Vps8; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR016902; VPS41.
DR   InterPro; IPR045111; Vps41/Vps8.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12616; VACUOLAR PROTEIN SORTING VPS41; 1.
DR   PANTHER; PTHR12616:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG; 1.
DR   Pfam; PF00637; Clathrin; 1.
DR   Pfam; PF00400; WD40; 1.
DR   PIRSF; PIRSF028921; VPS41; 1.
DR   SMART; SM00299; CLH; 1.
DR   SMART; SM00320; WD40; 2.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50236; CHCR; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|PIRNR:PIRNR028921};
KW   Transport {ECO:0000256|PIRNR:PIRNR028921};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   REPEAT          101..131
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..47
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   950 AA;  106330 MW;  32A8E78D9F32B10F CRC64;
     MSTAARRGHP PPHENGVGGH ADDEPDEDGE EEEEEEGEGE VEDDEEEEPR LKYQRLGGSV
     PAIVSTDAAA AIAVADRMVA LGTHNGTLHI LDFQGNQVKE IAAHTATIND ISFDADGEYI
     GSCSDDGTVV ISSLFTDEKL KFEYHRPMKA IALDPNYYNN YRRFATGGLA GQVLVLTKKS
     WGGGYHKKVL RDGEGPIHSM KWRTDLLAWA NDAGVKVHDM KTDKGIAFIE RPKGIPRPEF
     LLPQLVWQDD TILVIGWGTS VKIAAIRTDS SQGLNGIQRS ITASNEKYVD IVGSFQTGYH
     ISGIAPFGDL LVVLAYIPEE EDRENSFSNS VPSRQGTAQR PEIHLVSWKN DELTTDALPI
     HGYEHYKAKD YALAHAPFSG SSNAGGQWAA GDEPLYYIVS PKDIVVAKPR DAEDHISWLL
     QHGWHEKALA AVEAGQGRTE LLDEVGSRYL DHLIIERKYA EAARLCPKLL RGSPSAWERW
     VFHFAHLRQL AVLVPYIPTE NPQLSDTAYE VALVALTTNP SFHELLLTTV KKWPPTLYSA
     SPVISAIEPQ LNSSSMTDSL KEALAELYVI NSQYDKALSL YAELLKPEVF EFIEKHNLHD
     AIHDKVVNLM ILDSKRTVNL LIQHRDTIPP NEVVGQLLHA SKSCDKRHLL HLYLHALFET
     DMNAGKDYHD MQVELYAEYE PRMLIPFLRT SQHYRLDKAY EIFAQKELVR EQVFVLGRMG
     NAKEALSTII NKLEDIQEAV EFVMEQHDDE LWEELIRQCL QKPEMVGMLL EHTVGNLDPL
     YIVSLVPDGL EIPRLRDRLV KIVTDYRTET SLRHGCNDIL KADCVNLLVK YYHEARRGVY
     MASMDEEVTG TRVAEGSSRA NERSSSLRAL EIKSRTRCGA RCCLCFDPLS IQDISVIVFY
     CCHAYHTSCL EGGLDLMKSN SSTQDSDEDD EGTPSGESRM RCVLCTTAAA
//