ID I1PXK2_ORYGL Unreviewed; 426 AA.
AC I1PXK2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=MHD domain-containing protein {ECO:0000259|PROSITE:PS51072};
OS Oryza glaberrima (African rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA05G0210000.1, ECO:0000313|Proteomes:UP000007306};
RN [1] {ECO:0000313|Proteomes:UP000007306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA Zuccolo A.;
RT "The complete genome of Oryza glaberrima.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORGLA05G0210000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPI-coated vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004347}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004347}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004347}.
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|PIRNR:PIRNR005992}.
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DR AlphaFoldDB; I1PXK2; -.
DR STRING; 4538.I1PXK2; -.
DR EnsemblPlants; ORGLA05G0210000.1; ORGLA05G0210000.1; ORGLA05G0210000.
DR Gramene; ORGLA05G0210000.1; ORGLA05G0210000.1; ORGLA05G0210000.
DR eggNOG; KOG0937; Eukaryota.
DR HOGENOM; CLU_026996_0_0_1; -.
DR OMA; IWIESMI; -.
DR Proteomes; UP000007306; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0030663; C:COPI-coated vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd09250; AP-1_Mu1_Cterm; 1.
DR CDD; cd14835; AP1_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR PANTHER; PTHR10529:SF338; OS05G0543100 PROTEIN; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 2.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00990; CLAT_ADAPTOR_M_1; 1.
DR PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 172..426
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 426 AA; 48770 MW; 736E458720E4E078 CRC64;
MAAGAVSALF LLDIKGRVLV WRDYRGDVSA LQAERFFTKL LDKESDAEVL SPVVHDDAGV
SYMFIQHNNV FLLTASRQNC NAASILLFLH RVVDVFKHYF EELEEESLRD NFVVVYELLD
EMMDFGYPQY TEAMILSEFI KTDAYRMEVT QRPPMAVTNA VSWRSEGIRY KKNEVFLDVV
ESVNILVNSN GQIVRSDVIG ELKMRTFLSG MPECKLGLND RVLLEAQGRT TKGKAIDLDD
IKFHQCVRLA RFENDRTISF IPPDGSFDLM TYRLSTQVKP LIWVEAQVEK HSRSRIQITV
KTRSQFKERS TATNVEIEVP VPEDSTNPNI RTSMGSAAYA PERDAMVWKI KSFPGGKEYM
CRAEFSLPSI TSEDGMPEKK APIRVKFEIP YFTVSGIQVR YLKIIERVDI RPFLGFDTSQ
WLVNMS
//
