GenomeNet

Database: UniProt
Entry: I1RJ96_GIBZE
LinkDB: I1RJ96_GIBZE
Original site: I1RJ96_GIBZE 
ID   I1RJ96_GIBZE            Unreviewed;      1008 AA.
AC   I1RJ96; A0A098DK17;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   16-JAN-2019, entry version 52.
DE   RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE            EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN   Name=FG03904.1 {ECO:0000313|EnsemblFungi:CEF78802};
GN   ORFNames=FGRAMPH1_01T13999 {ECO:0000313|EMBL:CEF78802.1};
OS   Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
OS   (Wheat head blight fungus) (Fusarium graminearum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
OC   Fusarium.
OX   NCBI_TaxID=229533 {ECO:0000313|EMBL:CEF78802.1, ECO:0000313|Proteomes:UP000070720};
RN   [1] {ECO:0000313|EnsemblFungi:CEF78802, ECO:0000313|Proteomes:UP000070720}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084
RC   {ECO:0000313|EnsemblFungi:CEF78802,
RC   ECO:0000313|Proteomes:UP000070720};
RX   PubMed=17823352; DOI=10.1126/science.1143708;
RA   Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G.,
RA   Di Pietro A., Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G.,
RA   Antoniw J., Baldwin T., Calvo S.E., Chang Y.-L., DeCaprio D.,
RA   Gale L.R., Gnerre S., Goswami R.S., Hammond-Kosack K., Harris L.J.,
RA   Hilburn K., Kennell J.C., Kroken S., Magnuson J.K., Mannhaupt G.,
RA   Mauceli E.W., Mewes H.-W., Mitterbauer R., Muehlbauer G.,
RA   Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T., Qi W.,
RA   Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA   Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT   "The Fusarium graminearum genome reveals a link between localized
RT   polymorphism and pathogen specialization.";
RL   Science 317:1400-1402(2007).
RN   [2] {ECO:0000313|EnsemblFungi:CEF78802, ECO:0000313|Proteomes:UP000070720}
RP   GENOME REANNOTATION.
RC   STRAIN=PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084
RC   {ECO:0000313|EnsemblFungi:CEF78802,
RC   ECO:0000313|Proteomes:UP000070720};
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J.,
RA   Daboussi M.-J., Di Pietro A., Dufresne M., Freitag M., Grabherr M.,
RA   Henrissat B., Houterman P.M., Kang S., Shim W.-B., Woloshuk C.,
RA   Xie X., Xu J.-R., Antoniw J., Baker S.E., Bluhm B.H., Breakspear A.,
RA   Brown D.W., Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M.,
RA   Danchin E.G.J., Diener A., Gale L.R., Gardiner D.M., Goff S.,
RA   Hammond-Kosack K.E., Hilburn K., Hua-Van A., Jonkers W., Kazan K.,
RA   Kodira C.D., Koehrsen M., Kumar L., Lee Y.-H., Li L., Manners J.M.,
RA   Miranda-Saavedra D., Mukherjee M., Park G., Park J., Park S.-Y.,
RA   Proctor R.H., Regev A., Ruiz-Roldan M.C., Sain D., Sakthikumar S.,
RA   Sykes S., Schwartz D.C., Turgeon B.G., Wapinski I., Yoder O.,
RA   Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A., Kistler H.C.,
RA   Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
RN   [3] {ECO:0000313|EMBL:CEF78802.1, ECO:0000313|Proteomes:UP000070720}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PH-1 {ECO:0000313|EMBL:CEF78802.1}, and PH-1 / ATCC MYA-4620 /
RC   FGSC 9075 / NRRL 31084 {ECO:0000313|Proteomes:UP000070720};
RX   PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA   King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA   Hammond-Kosack K.E.;
RT   "The completed genome sequence of the pathogenic ascomycete fungus
RT   Fusarium graminearum.";
RL   BMC Genomics 16:544-544(2015).
RN   [4] {ECO:0000313|EnsemblFungi:CEF78802}
RP   IDENTIFICATION.
RC   STRAIN=PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084
RC   {ECO:0000313|EnsemblFungi:CEF78802};
RG   EnsemblFungi;
RL   Submitted (JAN-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose
CC         residues in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|RuleBase:RU000675,
CC         ECO:0000256|SAAS:SAAS01116863};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|RuleBase:RU003679, ECO:0000256|SAAS:SAAS00534244}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; HG970333; CEF78802.1; -; Genomic_DNA.
DR   RefSeq; XP_011321764.1; XM_011323462.1.
DR   STRING; 229533.XP_384080.1; -.
DR   EnsemblFungi; CEF78802; CEF78802; FGRRES_03904.
DR   GeneID; 23551184; -.
DR   KEGG; fgr:FGSG_03904; -.
DR   EuPathDB; FungiDB:FGRAMPH1_01G13999; -.
DR   eggNOG; KOG0496; Eukaryota.
DR   eggNOG; COG1874; LUCA.
DR   Proteomes; UP000070720; Chromosome 2.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.102.20.10; -; 1.
DR   Gene3D; 2.60.120.260; -; 2.
DR   Gene3D; 2.60.390.10; -; 1.
DR   InterPro; IPR018954; Betagal_dom2.
DR   InterPro; IPR037110; Betagal_dom2_sf.
DR   InterPro; IPR025972; BetaGal_dom3.
DR   InterPro; IPR036833; BetaGal_dom3_sf.
DR   InterPro; IPR025300; BetaGal_jelly_roll_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR019801; Glyco_hydro_35_CS.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421; PTHR23421; 1.
DR   Pfam; PF10435; BetaGal_dom2; 1.
DR   Pfam; PF13363; BetaGal_dom3; 1.
DR   Pfam; PF13364; BetaGal_dom4_5; 2.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SMART; SM01029; BetaGal_dom2; 1.
DR   SUPFAM; SSF117100; SSF117100; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000070720};
KW   Glycosidase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108888};
KW   Hydrolase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108869};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070720};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19   1008       Beta-galactosidase. {ECO:0000256|SAM:
FT                                SignalP}.
FT                                /FTId=PRO_5010124318.
FT   DOMAIN      393    569       BetaGal_dom2. {ECO:0000259|SMART:
FT                                SM01029}.
SQ   SEQUENCE   1008 AA;  110827 MW;  080861E1BDB598A4 CRC64;
     MKLSNFFLAA LAACGCHAVN IVPRGGRPSS IINNAYKREL LQDIVTFDEH SLFINGERVT
     MFSAEIHPFR LPVPSLYLDL FHKVKAMGFN MVSFYVDWAL LEGKPGEFRS EGSLDLQPFI
     DAAQEAGIYL LARPGPYINA EVSGGGFPGW LQRVKGFLRT NATDYLESTD NYVAKVGAII
     AKAQITNGGP VILYQPENEY SAAQGTPFPN HDYLKYVNDQ ARKAGIVVPL INNDAWQGGT
     GAPGTGPGAV DIYGHDGYPV GFDCTNPYKW PKDGLPTTWH AEHLKKSPNT PYSIIEFQGG
     AFDPPGGTGF DKCYELTNHE FARVFYKNNL AAGVTIFNIY MTWGGTNWGN LGHSDGYTSY
     DYGAAIKEDR TIAREKYSEI KLQGQFLAVS PNYAVATASN FTTTKYTTNK NIAVTALTTK
     KDDAFYVVRH EDYRTTSSAS YMLKVKTSVG QLTIPQLGGS LSLSGRDSKI HVVDYPVGKY
     KVLYSTAEVF TWKDLGDKTV LVLYGGPNEL HEFAIKSSSN LKVIEGDGVK METKKGASVF
     QFKTSSKRRI VQIGSLHVYL LDRNAAYNYW VPTIPGKGDR AAFGSSVMNP KAVIFNGAHL
     IRSVAVKGSQ LSVQADFNAT SSLEIIGAPK GTSRLLINGK DTPYKKSKIG NWLVNPSVSL
     PDVKISDLKS LDWKYVDSLP EAKKDYDDSK WPDANLKKTF NSKWPLNNSV SLYGGDYGFH
     SGALLFRGHF TADGAESKFK VWTFGGMSYG SSVWLDDKFL GSFVGSGPRN NDTTTYSLPK
     IQKGKKYVLT VIVDNMGLNG NWVPGLEEGK QPRGILDWSL ESSSGKETTK ISKWKITGNL
     GGEDYVDKFR GPRNEGGFFF ERQGYHLPSP PLSDFKSGSP FKGISRPGVA FYTANLKLNL
     PSDNFDIPLS FEFKNNTAST GSYRALLYVN GFQYGRYVSH VGPQSVFPVP EGVFNYRGDN
     WIGIGLWALD KGANVDGLSL KAGVPVQTGR EPVKFVKGPK YAHRRGAY
//
DBGET integrated database retrieval system