ID I1RPP0_GIBZE Unreviewed; 2030 AA.
AC I1RPP0; A0A098E2X0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Chromosome 3, complete genome {ECO:0000313|EMBL:CEF87433.1};
GN Name=FG06016.1 {ECO:0000313|EnsemblFungi:CEF87433};
GN ORFNames=FGRAMPH1_01T19295 {ECO:0000313|EMBL:CEF87433.1};
OS Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=229533 {ECO:0000313|EMBL:CEF87433.1, ECO:0000313|Proteomes:UP000070720};
RN [1] {ECO:0000313|EnsemblFungi:CEF87433, ECO:0000313|Proteomes:UP000070720}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1
RC {ECO:0000313|Proteomes:UP000070720}, and PH-1 / ATCC MYA-4620 / FGSC
RC 9075 / NRRL 31084 {ECO:0000313|EnsemblFungi:CEF87433};
RX PubMed=17823352; DOI=10.1126/science.1143708;
RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT "The Fusarium graminearum genome reveals a link between localized
RT polymorphism and pathogen specialization.";
RL Science 317:1400-1402(2007).
RN [2] {ECO:0000313|EnsemblFungi:CEF87433, ECO:0000313|Proteomes:UP000070720}
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1
RC {ECO:0000313|Proteomes:UP000070720}, and PH-1 / ATCC MYA-4620 / FGSC
RC 9075 / NRRL 31084 {ECO:0000313|EnsemblFungi:CEF87433};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [3] {ECO:0000313|EMBL:CEF87433.1, ECO:0000313|Proteomes:UP000070720}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1
RC {ECO:0000313|Proteomes:UP000070720}, and PH-1
RC {ECO:0000313|EMBL:CEF87433.1};
RX PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA King R., Urban M., Hammond-Kosack M.C., Hassani-Pak K.,
RA Hammond-Kosack K.E.;
RT "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT graminearum.";
RL BMC Genomics 16:544-544(2015).
RN [4] {ECO:0000313|EnsemblFungi:CEF87433}
RP IDENTIFICATION.
RC STRAIN=PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084
RC {ECO:0000313|EnsemblFungi:CEF87433};
RG EnsemblFungi;
RL Submitted (JAN-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
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DR EMBL; HG970334; CEF87433.1; -; Genomic_DNA.
DR RefSeq; XP_011324635.1; XM_011326333.1.
DR STRING; 229533.I1RPP0; -.
DR EnsemblFungi; CEF87433; CEF87433; FGRRES_06016.
DR GeneID; 23553163; -.
DR KEGG; fgr:FGSG_06016; -.
DR VEuPathDB; FungiDB:FGRAMPH1_01G19295; -.
DR eggNOG; KOG1998; Eukaryota.
DR HOGENOM; CLU_000595_0_1_1; -.
DR InParanoid; I1RPP0; -.
DR OrthoDB; 8258at2759; -.
DR Proteomes; UP000070720; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08679; C2_DOCK180_related; 1.
DR CDD; cd11684; DHR2_DOCK; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF10; MYOBLAST CITY, ISOFORM B; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000070720};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 7..87
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 611..793
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1441..1853
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 89..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1775..1794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1847..1880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1907..2030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..104
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1776..1791
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1858..1880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1928..1948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1949..1963
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2030 AA; 226247 MW; 779B28B6F1DD8724 CRC64;
MPWQPLPRIA FAVATFPFPA SSPADLPLEI GDELYIIEET PDGNWLRGYL VAPPSLLAGL
TSVKGQTLEA RVFSGIFPRS CVEVREMLGE PDDDDEDDDA ASDGPAIDGD MPRASDSAKS
GVTNNSARKS RKEGNRSTIS SGRTPFRELP NGTLGNLSVP VIRDPDAPRP AAPVPMLKIG
DETPTSLSEP LIDEIASCLR EWHSTNLHEL LLSRQYGRLD QLSQLITSLN LHRQQFLYNV
LTAHEYDRLR EKTVWDLVRV NKLCGGEVIV RDPEARGRVL TADDCIVKVT KLQSVMSLLD
EPPQSTSELT ALHHLMVDIK GFAGASIEET SLVFYLVSKP AYGQPSILSE AFTVRIPAGG
TLVNLAKHVQ TKTLFTDLSS QDVGDVPSAE AELFLVVKVL ASHQIIPPQS LSRSGTAPSA
SYSRDPTKPN SSGGIKSRRS LMWGSKSSRG ASRGSPVSRM DAVAEQYDGR HSMSGSESRE
GSGPPSTAGS KTGSPTDGTQ TADRMIGLGV LRLNPIMKQD DEVEHLMSIW SSSLRHTGEN
DADDWEPLVK ELLDSPSGHY EKSRRGDRLQ LQLRSFNHSD ADILIKSTPT MLSGVAKTNK
MGFSGAPTRP RSDIYFTLND AILGKQNLLS RFGGSATAMP SSVHGNNLQI TLEVRKTSGE
RIDNCIFASS NTEPLSTFKS IAAERGEPWN QTLRLSLAPS DVSQAHIVMF VSDMPNPPFA
IAHIPLWDQG AFIRDGRHAL LLYKIDEHTS TAQPGPTGKG GYLSLLWNPQ GKDDDTADAN
GPLAVLRTET YLCSTRFSQD RVILGLLKWR DLQREEVPGV LKQLIFVPEI EVVKLLNDVL
DGLFGILVEY SGSHEFEDLV FTALVRVLGI VHDRRFNLGP LVDQYAENLF NYPFSTPCLM
RSFTRLLQNP SEPEIARKLR ATFKVVRHIL KFITHARNQQ KEKEAGIGIT SNTTGFTREL
RAIFKALDAM MRNTAPALVG TQTLAVQHFH QWLPELAGLL NTEEILHIAI DFMDSCTDVK
GKLILYKLVL IINYSKLDLF AHPDQKLALS TNTVRWITPH WGHTAEVTDQ WRDQIRLCCS
VLASQIDYLG SEIPDHIPKI IDSYLAILAA PSKPKDRLSL LFPSSYPFPT KPVNDDLQFD
EALVELSAIL SSISNSPSGM QLELAEDDLT TLLENLLRVH MSILKGEAYP LEWLSVHIHH
HKSTMRTLEY LAGTMLESFL PEPEEAESFN TELWKLFFTT LLKLVGSTSL ALETFPEQKR
RAVWKIAGDV REHGAELLRR TWEAIGWETS SDERSRYNLS KMGGYQVQYV PALVGPIVEL
CLSVHEGLRR MAVEVLQTMI VSEWTLSEDL SIIQTETIDR LDLFFKEKPL TESILQKLFI
HELLERFEPL VDIPDEPLYT AIREFVGTID EFLDLLVAVY SSDDTGEASS LINHLRLMEF
LRDMQKEEIF VRYVHQLADL QAESRNHTEA GLALRLHADL YEWDPTSQTP ALPDPEFPAQ
TQFERKERLY FDMIKYFEEG DSWSHALAAY KELQVQYESN IFDFLKLART ERAIATIYET
ISKSDKIIPK YFKVVYKGLG FHANLRDKEF IYEGSPSERA SAFTDRMQEQ HPAAQIVTGG
DVDDVEGQFL VVSAVTPHRD LGHQVFQRAR VPQVIRDFLL SSHPQTFSIS TRRNTTGPVK
EHSAEKLVFT TADAFPTILR RSEVVDAQEI TLSAHETGLE RIVRKTQEMT ALEHRVTEGN
GDHAQLLLDA VSVSVNPTSE NSVACYRQLL PERKEADEDA EEEEDQEAPE VELTPQDSAI
KMALVDHAIM IKRCLAMFSR SSNELLTQKH DELHRCFEST FAPEIAHFTP PQPQRELVAT
PSPTWKRSSR SSSASPKNKN VGIVVNGVTA EEASVIRPVS KRGTRLSFLG GSKKKEPELP
TEPEEVNGDI ETASNLSRSL SQGQSKEQGR RHSFFRAPSQ DEKHPESAGV LSGRGSFDQQ
FGGGDNSNHN DKPVENKLAS KKGSVRKRFS MLKLGRKGKG NGMMGSLDEE
//
