ID I1XJA8_METNJ Unreviewed; 444 AA.
AC I1XJA8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Membrane fusion protein (MFP) family protein {ECO:0000256|RuleBase:RU365093};
GN OrderedLocusNames=Q7A_1653 {ECO:0000313|EMBL:AFI84477.1};
OS Methylophaga nitratireducenticrescens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=754476 {ECO:0000313|EMBL:AFI84477.1, ECO:0000313|Proteomes:UP000009144};
RN [1] {ECO:0000313|EMBL:AFI84477.1, ECO:0000313|Proteomes:UP000009144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM1 {ECO:0000313|EMBL:AFI84477.1,
RC ECO:0000313|Proteomes:UP000009144};
RX PubMed=22815445; DOI=10.1128/JB.00726-12;
RA Villeneuve C., Martineau C., Mauffrey F., Villemur R.;
RT "Complete genome sequences of Methylophaga sp. strain JAM1 and Methylophaga
RT sp. strain JAM7.";
RL J. Bacteriol. 194:4126-4127(2012).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU365093}; Single-pass membrane protein
CC {ECO:0000256|RuleBase:RU365093}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477, ECO:0000256|RuleBase:RU365093}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003390; AFI84477.1; -; Genomic_DNA.
DR RefSeq; WP_014706850.1; NC_017857.3.
DR AlphaFoldDB; I1XJA8; -.
DR STRING; 754476.Q7A_1653; -.
DR KEGG; mej:Q7A_1653; -.
DR PATRIC; fig|754476.3.peg.1634; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_023976_1_1_6; -.
DR OrthoDB; 9775513at2; -.
DR Proteomes; UP000009144; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR010129; T1SS_HlyD.
DR NCBIfam; TIGR01843; type_I_hlyD; 1.
DR PANTHER; PTHR30386:SF17; ALKALINE PROTEASE SECRETION PROTEIN APRE; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR PRINTS; PR01490; RTXTOXIND.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU365093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU365093}; Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:AFI84477.1};
KW Membrane {ECO:0000256|RuleBase:RU365093};
KW Protease {ECO:0000313|EMBL:AFI84477.1};
KW Transmembrane {ECO:0000256|RuleBase:RU365093};
KW Transmembrane helix {ECO:0000256|RuleBase:RU365093};
KW Transport {ECO:0000256|RuleBase:RU365093}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365093"
FT DOMAIN 35..399
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 241..283
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 444 AA; 49262 MW; 51585F6E5301A70A CRC64;
MQNENTKPQN KDVLTSLNKD INKYTRLGWG IVIAGFGGFL VWASLAPLDQ GVPLNGKVSV
ATKRKAVQYQ DGGTVEDILV KEGDLVMAGE VLVRMNSVQA RANAETNRVQ YYIAKAAEAR
LIAERDDLQQ IEFPKMLKDV ADYPRISNYL GSQTEIFTSR RSALQSELSV IDENIKGLIS
KAEGLQASRA NKLEQLKFLG EQLKGVRELE KEGYVARNRL LELEQTMAQI NATIAEDVGN
IAQARSQVAE LKLSQLKLRQ EYKAEVREQL SEVQKQVDAL GNQLTGLDYD LEKVLVRAPV
SGTVVGMNVF TEGAVVAPGF TMMEIVPRDD SLVVEGQLAV HLIDKVSPGL PVELMFTAFN
RNLTPHIPGE VTQVSADRLI DETDGSPYYQ LIAKVSPEGI EMMPDLRLQP GMPVEMFVKT
GERTMLNYLL KPIIDRLKLS MSEE
//
