ID I1XMF5_METNJ Unreviewed; 830 AA.
AC I1XMF5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:AFI85574.1};
GN OrderedLocusNames=Q7A_2792 {ECO:0000313|EMBL:AFI85574.1};
GN ORFNames=CDW43_12360 {ECO:0000313|EMBL:AUZ85311.1};
OS Methylophaga nitratireducenticrescens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=754476 {ECO:0000313|EMBL:AFI85574.1, ECO:0000313|Proteomes:UP000009144};
RN [1] {ECO:0000313|EMBL:AFI85574.1, ECO:0000313|Proteomes:UP000009144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM1 {ECO:0000313|EMBL:AFI85574.1,
RC ECO:0000313|Proteomes:UP000009144};
RX PubMed=22815445; DOI=10.1128/JB.00726-12;
RA Villeneuve C., Martineau C., Mauffrey F., Villemur R.;
RT "Complete genome sequences of Methylophaga sp. strain JAM1 and Methylophaga
RT sp. strain JAM7.";
RL J. Bacteriol. 194:4126-4127(2012).
RN [2] {ECO:0000313|EMBL:AFI85574.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JAM1 {ECO:0000313|EMBL:AFI85574.1};
RX PubMed=23148104; DOI=10.1099/ijs.0.044545-0;
RA Villeneuve C., Martineau C., Mauffrey F., Villemur R.;
RT "Methylophaga nitratireducenticrescens sp. nov. and Methylophaga frappieri
RT sp. nov., isolated from the biofilm of the methanol-fed denitrification
RT system treating the seawater at the Montreal Biodome.";
RL Int. J. Syst. Evol. Microbiol. 63:2216-2222(2013).
RN [3] {ECO:0000313|EMBL:AFI85574.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JAM1 {ECO:0000313|EMBL:AFI85574.1};
RA Villeneuve C., Villemur R.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AUZ85311.1, ECO:0000313|Proteomes:UP000238402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GP59 {ECO:0000313|EMBL:AUZ85311.1,
RC ECO:0000313|Proteomes:UP000238402};
RA Villemur R.;
RT "The sequence of the genome of Methylophaga nitratireducenticrescens GP59
RT and its two plasmids.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003390; AFI85574.1; -; Genomic_DNA.
DR EMBL; CP021973; AUZ85311.1; -; Genomic_DNA.
DR AlphaFoldDB; I1XMF5; -.
DR STRING; 754476.Q7A_2792; -.
DR KEGG; mej:Q7A_2792; -.
DR PATRIC; fig|754476.3.peg.2739; -.
DR eggNOG; COG3829; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_6; -.
DR Proteomes; UP000009144; Chromosome.
DR Proteomes; UP000238402; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 214..267
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 275..321
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 346..400
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 429..560
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 569..824
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 830 AA; 94913 MW; 5C734E6B2A090C3B CRC64;
MGFAKWLWLY SCIVIILITA ISIISWNGLS SLYNSIYDQS DIQNNKAIKI TKISQLLNEN
YSLAISLNQP SQQRVLPYDL VENKNIISKI KRNINEITRS TESLLKISQN EVEINLINEF
QKRRKEWLKI LLLSQRQDKA HITDNEFGIL QDNIRKNATA TVESLYRIRE LNDNKAAELL
LQVDKNYKNT LITLSTAILI CIIAASLFSI STINYIRTVV KRVIRFAETM SYGDWSNPIN
NINEPGEIGI LLTHLEQMRG RLHSLFTQNK QVENKATKLL LAVNQSNSTV LMTDLSTKII
YVNEAFTQTT GYKAEEVIGR TPKILQSNKT PEEVYKDLWK NLRQGITWTG ELINRCKDGT
LITEVVKISP IKNISGETEG YMAVKDNITE LKKAHQHIEK MAYSDALTDL PNRHRFIREL
KTLLNKGNNS FSILFIDLNN FKQINDSKGH NVGDSILKTI SQRLSDCCKN QFLLARVGGD
EFVIISLFIE EFMIKRLVNN LHRTLSMPIY IDDYQYILGA SIGISNFPEH GKTSQDILRR
ADIAMYQSKI KNLPYCIYNK EMESQIQREL LILQRFELAL STSEGLNIHL QPQFSLKDKA
LIGAEVLLRW HDNILGNVSP GEFIKIAENS GLIFKLDKWV IEHTLDYLSE CRSVAIFSGR
IAINISSQTL ENPIFSSWMK NRIKNTKVDS KYIELEITET GLMNDPDKAL QNIIKLKSFG
ISVSIDDFGT GYSSLAYLRR FNADKLKIDK SFIDHIHTSK TDQSIVLATI DLAHSLGMKA
LAEGIENEDQ EQILVELGCD FAQGYYYAKP MPKKEFTDHY LINNEIIHTQ
//
