ID I1YHF8_METFJ Unreviewed; 645 AA.
AC I1YHF8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=NADH-ubiquinone oxidoreductase chain L {ECO:0000313|EMBL:AFJ02351.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:AFJ02351.1};
DE Flags: Precursor;
GN OrderedLocusNames=Q7C_1200 {ECO:0000313|EMBL:AFJ02351.1};
OS Methylophaga frappieri (strain ATCC BAA-2434 / DSM 25690 / JAM7).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=754477 {ECO:0000313|EMBL:AFJ02351.1, ECO:0000313|Proteomes:UP000009145};
RN [1] {ECO:0000313|EMBL:AFJ02351.1, ECO:0000313|Proteomes:UP000009145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM7 {ECO:0000313|EMBL:AFJ02351.1,
RC ECO:0000313|Proteomes:UP000009145};
RX PubMed=22815445; DOI=10.1128/JB.00726-12;
RA Villeneuve C., Martineau C., Mauffrey F., Villemur R.;
RT "Complete genome sequences of Methylophaga sp. strain JAM1 and Methylophaga
RT sp. strain JAM7.";
RL J. Bacteriol. 194:4126-4127(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
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DR EMBL; CP003380; AFJ02351.1; -; Genomic_DNA.
DR RefSeq; WP_014703771.1; NC_017856.1.
DR AlphaFoldDB; I1YHF8; -.
DR STRING; 754477.Q7C_1200; -.
DR KEGG; mec:Q7C_1200; -.
DR PATRIC; fig|754477.3.peg.1180; -.
DR eggNOG; COG1009; Bacteria.
DR HOGENOM; CLU_007100_6_0_6; -.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000009145; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR Gene3D; 1.20.5.2700; -; 1.
DR InterPro; IPR018393; NADHpl_OxRdtase_5_subgr.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR003945; NU5C-like.
DR InterPro; IPR001516; Proton_antipo_N.
DR NCBIfam; TIGR01974; NDH_I_L; 1.
DR PANTHER; PTHR42829; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR PANTHER; PTHR42829:SF2; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:AFJ02351.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009145};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Ubiquinone {ECO:0000313|EMBL:AFJ02351.1}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..118
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 134..419
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 645 AA; 71416 MW; 851AF5B32F5904EB CRC64;
MTQNLLLALV LSPLFGCLIA GFLGRQIGRR NAHRVAIAGV AVAFALSVYV LKLVLVDGQY
FNATIYHWLQ AGSLSIEVGF MVDALTAVMM VVVTFVSFMV HIYTIGYMHE DPGYCRFFSY
LSLFTFAMLM LVMANNFMQL FFGWEAVGLV SYLLIGFWYK KPTAIYANLK AFLVNRVGDF
GFLLGIGAVL MYSGSLNYLE VFAQAPALAE RHITIWGDQS WSLMTVIGIL LFIGAMGKSA
QVPLHVWLPD SMEGPTPISA LIHAATMVTA GIFMVARMSP LYAYSETALA FIVIIGAITA
LFMGFLGLIQ NDIKRVIAYS TLSQLGYMTV ALGVSAYSAA IFHLFTHAFF KALLFLAAGS
VILAMHHQQD IRQMGGLRKY LPITYWTSVI GTLALIGAPG LAGFFSKDAI IEAVHASAMP
GAGFAYWALL IGVFVTALYS FRLLFLVFHG QSRFDAHGHP PHESPVVVTV PLILLAIPSI
FAGYLIGQMV FGDWLRDAIV VSPQTDVLNM LGYHGVWAFL WHGLQMPPFW LALAGVVTAW
FLYIRRPDLP ARLQHWGRWL WRILDNKYGF DHFNEKVFAG GARGLGSLLW QLGDKRLIDG
VLVNGSARLI GLAARFGRHV QSGYLYHYAF VMMIGVWLLL SWFVL
//
