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Database: UniProt
Entry: I2B4A1_SHIBC
LinkDB: I2B4A1_SHIBC
Original site: I2B4A1_SHIBC 
ID   I2B4A1_SHIBC            Unreviewed;       772 AA.
AC   I2B4A1; K6WM67;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   05-JUN-2019, entry version 40.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   Name=feoB {ECO:0000313|EMBL:AFJ45355.1};
GN   OrderedLocusNames=EBL_c02200 {ECO:0000313|EMBL:AFJ45355.1};
OS   Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC
OS   105725 / CDC 9005-74) (Escherichia blattae).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shimwellia.
OX   NCBI_TaxID=630626 {ECO:0000313|EMBL:AFJ45355.1, ECO:0000313|Proteomes:UP000001955};
RN   [1] {ECO:0000313|EMBL:AFJ45355.1, ECO:0000313|Proteomes:UP000001955}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74
RC   {ECO:0000313|Proteomes:UP000001955};
RX   PubMed=22843577; DOI=10.1128/JB.00829-12;
RA   Brzuszkiewicz E., Waschkowitz T., Wiezer A., Daniel R.;
RT   "Complete genome sequence of the B12-producing Shimwellia blattae
RT   strain DSM 4481, isolated from a cockroach.";
RL   J. Bacteriol. 194:4436-4436(2012).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CP001560; AFJ45355.1; -; Genomic_DNA.
DR   RefSeq; WP_002444766.1; NZ_BAHA01000036.1.
DR   STRING; 630626.EBL_c02200; -.
DR   EnsemblBacteria; AFJ45355; AFJ45355; EBL_c02200.
DR   KEGG; ebt:EBL_c02200; -.
DR   PATRIC; fig|630626.3.peg.227; -.
DR   KO; K04759; -.
DR   OMA; MEMPDYE; -.
DR   OrthoDB; 304844at2; -.
DR   BioCyc; SBLA630626:G1H59-215-MONOMER; -.
DR   Proteomes; UP000001955; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001955};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001955};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    282    306       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    312    331       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    343    367       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    387    409       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    421    447       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    453    473       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    511    529       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    664    685       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    722    742       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        3    169       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   772 AA;  83565 MW;  BEB9C158DF7D48DF CRC64;
     MKNLTIGLIG NPNSGKTTLF NQLTGSRQRV GNWAGVTVER KEGQFSTTDH KVTLVDLPGT
     YSLTTISSQT SLDEQIACHY ILSGDADLLI NVVDASNLER NLYLTLQLIE LGIPCIVALN
     MLDIAEKQHI QIDADALAAR LGCPVVPIIS TRGRGIDSLK LAIDRRHQNQ NIELVHYAKP
     LQREAAWLAG EMPAQIPARQ RNWLAIQMLE GDIYSRNYAG EAQEKLDVAR ARLADEIDDP
     ALHIADARYQ SISAICEAVS NTLTSGPNKL TAAMDKIILN RVLGLPIFLL VMYLMFLLAI
     NIGGALQPIF DGGSVAIFIH GIQWLGATLH FPQWLTIFLA QGIGGGINTV LPLVPQIGMM
     FLFLSFLEDS GYMARAAFVM DRLMQSLGLP GKSFVPLIVG FGCNVPSVMG ARTLDAPRER
     LMTIMMAPFM SCGARLAIFA VFAAAFFGQS GALVVFSLYI LGIVMAILTG LMLKFTILRG
     EASPFVMELP VYHVPHLKGL LLQTWQRLKG FVLRAGKVIV IVSVFIGALN SFSFSGKAVD
     NINDSALASV SKVLTPLLAP IGVHEDNWQA TIGLFTGAMA KEVVVGTLNT LYTAENIHEE
     AFDPASFSLT GELSDALQET WTSLVDTFSL SVLANPIEAS KGDGDMGTGT MGVMNAKFGS
     DAAAYSYLIF VLLYTPCIAV MGAIAREASR GWVMFAVFWG MDIGYSLATL NYQIASFSAH
     PQYSLVCILA VILFNVVVIG LLRRSRSLVD VNLLTQGKPV SSCCQNSSGD CH
//
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