ID I2F407_9BACT Unreviewed; 283 AA.
AC I2F407;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Metal-dependent hydrolase, beta-lactamase superfamily III {ECO:0000313|EMBL:AFK06660.1};
GN ORFNames=Theba_0954 {ECO:0000313|EMBL:AFK06660.1};
OS Mesotoga prima MesG1.Ag.4.2.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae; Mesotoga.
OX NCBI_TaxID=660470 {ECO:0000313|EMBL:AFK06660.1, ECO:0000313|Proteomes:UP000002881};
RN [1] {ECO:0000313|EMBL:AFK06660.1, ECO:0000313|Proteomes:UP000002881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mesG1.Ag.4.2 {ECO:0000313|Proteomes:UP000002881};
RX PubMed=22798451;
RA Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C.,
RA Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N.,
RA Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L.;
RT "Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima
RT MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date.";
RL Genome Biol. Evol. 4:700-708(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003532; AFK06660.1; -; Genomic_DNA.
DR RefSeq; WP_014730681.1; NC_017934.1.
DR AlphaFoldDB; I2F407; -.
DR STRING; 660470.Theba_0954; -.
DR KEGG; mpg:Theba_0954; -.
DR eggNOG; COG1234; Bacteria.
DR HOGENOM; CLU_1000640_0_0_0; -.
DR Proteomes; UP000002881; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR46504; TRNASE Z TRZ1; 1.
DR PANTHER; PTHR46504:SF2; TRNASE Z TRZ1; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AFK06660.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002881}.
FT DOMAIN 35..66
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
SQ SEQUENCE 283 AA; 32425 MW; DA8790A53583C873 CRC64;
MEFQIFSKAL YSTWILYRPE RVLFDVGEGI STVLGNSVYA IKDIFLTHGH VDHISGLWGL
INTRNTAMGD RNKQLRINFP SGNRAIEAYL DFIIGMNPRL RYNMILNPLN VGDEVYLRTA
GSFRRHVTPF KVKHTIGEIS YGYHVYEERR KLKDIYGGLP SKEIASVVKE KGREAITDTY
LQKIVTISGD TFALPPEVIS NSETLLHECT FLVGKDRRNQ NHSSIDEVIC TVRQSSGIKR
LILYHISGRY TSKIKKWHNI IKKELEGTGT EVFLVHPEHV FEL
//
